Annoni Andrea Daniele, Mancini Maria E, Andreini Daniele, Formenti Alberto, Mushtaq Saima, Nobili Enrica, Guglielmo Marco, Baggiano Andrea, Conte Edoardo, Pepi Mauro
Centro Cardiologico Monzino, IRCCS, Milan, Italy.
Department of Cardiovascular Sciences and Community Health, University of Milan, Milan, Italy.
J Med Imaging Radiat Oncol. 2017 Oct;61(5):614-621. doi: 10.1111/1754-9485.12608. Epub 2017 Mar 27.
Multidetector Computed Tomography Angiography (MDCTA) is presently the imaging modality of choice for aortic disease. However, the effective radiation dose and the risk related to the use of contrast agents associated with MDCTA is an issue of concern. Aim of this study was to assess image quality of a low dose ECG-gated MDCTA of thoracic aorta using different concentration contrast media without tailored injection protocol.
Two-hundred patients were randomised into four different scan protocols: Group A (Iodixanol 320 and 80 Kvp tube voltage), Group B (Iodixanol 320 and 100 Kvp tube voltage), Group C (Iomeprol 400 and 80 Kvp tube voltage) and Group D (Iomeprol 400 and 100 Kvp tube voltage). Image quality, noise, signal-to-noise ratio (SNR), contrast-to-noise ratio (CNR) and effective dose (ED) were compared among groups.
No significant differences in image noise, SNR and CNR between groups with the same tube voltage. Significant differences in SNR and CNR were found among groups with 80 kV versus groups using 100 kV but without differences in terms of image quality. ED was significantly lower in groups with 80 kV.
Multidetector Computed Tomography Angiography protocols using 80 kV and low concentration contrast media are feasible without need of tailored injection protocols.
多排螺旋计算机断层血管造影(MDCTA)目前是主动脉疾病的首选成像方式。然而,MDCTA相关的有效辐射剂量以及与使用造影剂相关的风险是一个令人关注的问题。本研究的目的是在不采用定制注射方案的情况下,评估使用不同浓度造影剂的低剂量心电图门控胸主动脉MDCTA的图像质量。
200名患者被随机分为四种不同的扫描方案:A组(碘克沙醇320和80千伏管电压)、B组(碘克沙醇320和100千伏管电压)、C组(碘美普尔400和80千伏管电压)和D组(碘美普尔400和100千伏管电压)。比较各组之间的图像质量、噪声、信噪比(SNR)、对比噪声比(CNR)和有效剂量(ED)。
相同管电压组之间的图像噪声、SNR和CNR无显著差异。80千伏组与100千伏组之间的SNR和CNR存在显著差异,但图像质量方面无差异。80千伏组的ED显著更低。
使用80千伏和低浓度造影剂的多排螺旋计算机断层血管造影方案是可行的,无需定制注射方案。