Darré Tchin, Folligan Koué, Kpatcha Tchilabalo Matchonna, Kanassoua Kokou, Sewa Edoe, Daré Sassil, Tengue Kodjo, Amégbor Koffi, Napo Koura Gado
Department of Pathology, the University Teaching Hospital of Lomé, Togo. Email:
Asian Pac J Cancer Prev. 2017 Feb 1;18(2):491-494. doi: 10.22034/APJCP.2017.18.2.491.
Background: Urological cancers are an important public health issue and pose problems with diagnosis and adequate management in developing countries. Our aim was to determine and report epidemiological and histological features of urological cancers in Togo. Materials and methods: A retrospective descriptive study was conducted of cases of urological cancers observed in the laboratory of pathological anatomy of the CHU Tokoin over the last 4 years (2012-2016). The parameters studied were frequency, age, sex, sites of development and histological type. Results: Epidemiological data were collected for 182 cases, representing 16.4% of all cancers (1108 cases). The annual frequency was 45.5±1.1 cases on average. The male:female sex ratio was 8.6 with a mean age of 60.2 years. Regarding location, in decreasing order of frequency, the tumors were found in the prostate (n=121 cases; 66.5%), bladder (n=28; 15.4%), kidney (n=19; 10.4%), testis (n=10; 5%), penis (n=3; 1.7%) and scrotum (n=1; 0.5%). Histologically, prostate cancers were predominantly adenocarcinomas (n=116 cases; 95.8%) with a Gleason score of 6 (n=46; 39.7%) predominant. Bladder cancers were mainly squamous cell carcinomas (n=11; 39.3%) followed by transitional carcinomas (n=9 cases; 32.1%) and adenocarcinomas (n=7; 25%). Kidney cancers were predominantly nephroblastomas (n=10, 52.6%) in children and clear cell carcinomas (n=8 cases; 42.1%) in adults. Testicular cancers were Burkitt lymphomas in 5 cases. The cases of penis and scrotum cancers were all squamous cell carcinomas. Conclusion: Urological cancers are experiencing an upsurge in frequency in Togo, dominated by prostate cancer, with a high frequency of squamous cell carcinoma of the bladder due to endemic bilharziasis.
泌尿系统癌症是一个重要的公共卫生问题，在发展中国家的诊断和充分管理方面存在问题。我们的目的是确定并报告多哥泌尿系统癌症的流行病学和组织学特征。材料与方法：对过去4年（2012 - 2016年）在托科因大学医院病理解剖实验室观察到的泌尿系统癌症病例进行回顾性描述性研究。研究的参数包括发病率、年龄、性别、发病部位和组织学类型。结果：收集了182例病例的流行病学数据，占所有癌症（1108例）的16.4%。年平均发病率为45.5±1.1例。男女比例为8.6，平均年龄为60.2岁。关于发病部位，按发病率从高到低排序，肿瘤分别位于前列腺（n = 121例；66.5%）、膀胱（n = 28例；15.4%）、肾脏（n = 19例；10.4%）、睾丸（n = 10例；5%）、阴茎（n = 3例；1.7%）和阴囊（n = 1例；0.5%）。组织学上，前列腺癌主要为腺癌（n = 116例；95.8%），Gleason评分为6分的占主导（n = 46例；39.7%）。膀胱癌主要为鳞状细胞癌（n = 11例；39.3%），其次是移行细胞癌（n = 9例；32.1%）和腺癌（n = 7例；25%）。儿童肾癌主要为肾母细胞瘤（n = 10例，52.6%），成人主要为透明细胞癌（n = 8例；42.1%）。5例睾丸癌为伯基特淋巴瘤。阴茎和阴囊癌病例均为鳞状细胞癌。结论：多哥泌尿系统癌症发病率呈上升趋势，以前列腺癌为主，由于地方性血吸虫病，膀胱癌鳞状细胞癌发病率较高。
