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不可修复性肩袖撕裂桥接重建中移植物的应用:一项系统评价

Graft Utilization in the Bridging Reconstruction of Irreparable Rotator Cuff Tears: A Systematic Review.

作者信息

Lewington Matthew R, Ferguson Devin P, Smith T Duncan, Burks Robert, Coady Catherine, Wong Ivan Ho-Bun

机构信息

Division of Orthopaedics, Department of Surgery, Dalhousie University, Halifax, Nova Scotia, Canada.

Department of Orthopaedics, University of Utah, Salt Lake City, Utah, USA.

出版信息

Am J Sports Med. 2017 Nov;45(13):3149-3157. doi: 10.1177/0363546517694355. Epub 2017 Mar 27.

Abstract

BACKGROUND

Rotator cuff tears are one of the most common conditions affecting the shoulder. Because of the difficulty in managing massive rotator cuff tears and the inability of standard techniques to prevent arthropathy, surgeons have developed several novel techniques to improve outcomes and ideally alter the natural history.

PURPOSE

To systematically review the existing literature and analyze reported outcomes to evaluate the effectiveness of using a bridging graft reconstruction technique to treat large to massive irreparable rotator cuff tears.

STUDY DESIGN

Systematic review.

METHODS

A systematic search of PubMed, EMBASE, CINAHL, and CENTRAL was employed with the key terms "tear," "allograft," and "rotator cuff." Eligibility was determined by a 3-phase screening process according to the outlined inclusion/exclusion criteria. Data in relation to the primary and secondary outcomes were summarized. The results were synthesized according to the origin of the graft and the level of evidence.

RESULTS

Fifteen studies in total were included in this review: 2 comparative studies and 13 observational case series. Both the biceps tendon and the fascia lata autograft groups had significantly superior structural integrity rates on magnetic resonance imaging at 12-month minimum follow-up when compared with their partial primary repair counterparts (58% vs 26%, P = .036; 79% vs 58%, P < .05), respectively. Multiple noncomparative case series investigating allografts, xenografts, and synthetic materials for bridging reconstruction of large to massive rotator cuff tears demonstrated high structural healing rates (74%-90%, 73%-100%, and 60%-90%, respectively). Additionally, both comparative studies and case series demonstrated a general improvement of patients' functional outcome scores.

CONCLUSION

Using a graft for an anatomic bridging rotator cuff repair results in improved function on objective testing and may be functionally better than nonanatomic or partial repair of large to massive rotator cuff tears. Allograft or xenograft techniques appear to be favorable options, given demonstrated functional improvement, imaging-supported graft survival, and lack of harvest complication risk. More high-quality randomized controlled studies are needed to further assess this technique.

摘要

背景

肩袖撕裂是影响肩部的最常见病症之一。由于处理巨大肩袖撕裂存在困难,且标准技术无法预防关节病,外科医生已开发出多种新技术以改善治疗效果并理想地改变其自然病程。

目的

系统回顾现有文献并分析报告的结果,以评估使用桥接移植重建技术治疗大型至巨大型不可修复肩袖撕裂的有效性。

研究设计

系统评价。

方法

采用系统检索PubMed、EMBASE、CINAHL和CENTRAL数据库,检索词为“撕裂”“同种异体移植物”和“肩袖”。根据概述的纳入/排除标准,通过三阶段筛选过程确定纳入资格。总结与主要和次要结果相关的数据。根据移植物的来源和证据水平对结果进行综合分析。

结果

本综述共纳入15项研究:2项比较研究和13项观察性病例系列。在至少12个月的随访中,与部分初次修复组相比,肱二头肌肌腱自体移植组和阔筋膜自体移植组在磁共振成像上的结构完整性率均显著更高(分别为58%对26%,P = 0.036;79%对58%,P < 0.05)。多项非比较性病例系列研究了用于大型至巨大型肩袖撕裂桥接重建的同种异体移植物、异种移植物和合成材料,显示出较高的结构愈合率(分别为74% - 90%、73% - 100%和60% - 90%)。此外,比较研究和病例系列均表明患者的功能结局评分总体有所改善。

结论

使用移植物进行解剖学桥接肩袖修复可改善客观测试中的功能,在功能上可能优于大型至巨大型肩袖撕裂的非解剖学或部分修复。鉴于已证明的功能改善、影像学支持的移植物存活以及无取材并发症风险,同种异体移植物或异种移植物技术似乎是有利的选择。需要更多高质量的随机对照研究来进一步评估该技术。

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