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68Ga-DOTA-RGD(αvβ3)PET/CT 显像在甲状腺球蛋白升高伴阴性碘扫描中的应用价值。

Usefulness of 68Ga-DOTA-RGD (αvβ3) PET/CT Imaging in Thyroglobulin Elevation With Negative Iodine Scintigraphy.

机构信息

From the Department of Nuclear Medicine, Postgraduate Institute of Medical Education & Research, Chandigarh, India.

出版信息

Clin Nucl Med. 2017 Jun;42(6):471-472. doi: 10.1097/RLU.0000000000001645.

Abstract

TENIS (thyroglobulin elevation with negative iodine scintigraphy) syndrome in patients with differentiated thyroid carcinoma is not a rare finding. In such patients, F-FDG PET/CT can help in disease evaluation. RGD tripeptide, used for imaging angiogenesis, may also help in disease detection in patients with negative radioiodine whole-body scan. We present 1 such case in whom Ga-RGD tripeptide imaging was helpful in disease detection in the setting of negative radioiodine whole-body scan.

摘要

分化型甲状腺癌患者的 TENIS(甲状腺球蛋白升高伴阴性碘闪烁扫描)综合征并不少见。在这些患者中,F-FDG PET/CT 有助于疾病评估。用于成像血管生成的 RGD 三肽也可能有助于发现全身放射性碘扫描阴性的患者中的疾病。我们报告了 1 例此类病例,在全身放射性碘扫描阴性的情况下,Ga-RGD 三肽成像有助于发现疾病。

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