Su P, Ding H, Zhang W, Duan G, Yang Y, Long J, Du L, Xie C, Jin C, Hu C, Sun Z, Duan Z, Gong L, Tian W
Wenhua Tian, PhD, Department of Health Services Management, the Second Military Medical University, No.800 Xiangyin Rd, Shanghai, 200433, China; Tel: +86-21-8187-1428; Fax: +86-21-8187-1428; Email address:
J Nutr Health Aging. 2017;21(4):362-369. doi: 10.1007/s12603-016-0777-z.
Although both obesity and hypertension are known risk factors for disability, the joint association of obesity and hypertension with risk of disability is unknown. This paper is aim to examine the joint association of obesity and hypertension with risk of disability.
Cross-sectional study with 8060 elderly community-dwelling individuals participating in the survey initiated by Shanghai Health and Family Planning Commission from March to September 2013. Obesity was measured using the body mass index (BMI) in World Health Organization (WHO) Asia criteria. Hypertension, based on the doctor's diagnosis, was obtained through face-to-face interview. Disability was measured using the self-reported physical self-maintenance scale (PSMS) and the instrumental activities of daily living (IADL) scale developed by Lawton and Brody.
A total of 8.97% of participants reported ADL disability, and 15.18% for IADL disability. After adjusting social demographics and chronic conditions, the risk of ADL disability was progressively greater in obese persons with hypertension (OR=1.40, 95% CI=1.05-1.89), underweight persons without hypertension (OR=2.05, 95% CI=1.29-3.25), and underweight persons with hypertension (OR=2.14, 95% CI=1.36-3.36). For IADL disability, only underweight persons with hypertension were significantly associated (OR=1.65, 95% CI=1.23-2.21).
Low or extremely high BMI, independent of its metabolic consequences, is a risk factor for disability among the elderly. Simple hypertension wasn't significantly associated with disability. In addition, having hypertension significantly increased the risk of ADL disability in obese individuals and IADL disability in underweight individuals.
尽管肥胖和高血压都是已知的导致残疾的风险因素,但肥胖和高血压与残疾风险的联合关联尚不清楚。本文旨在研究肥胖和高血压与残疾风险的联合关联。
采用横断面研究,对2013年3月至9月参加上海市卫生和计划生育委员会发起的调查的8060名社区老年居民进行研究。肥胖采用世界卫生组织(WHO)亚洲标准的体重指数(BMI)进行测量。高血压根据医生诊断,通过面对面访谈获得。残疾采用自我报告的身体自我维持量表(PSMS)和Lawton及Brody编制的日常生活活动能力(IADL)量表进行测量。
共有8.97%的参与者报告有日常生活活动(ADL)残疾,15.18%的参与者报告有IADL残疾。在调整社会人口统计学和慢性疾病因素后,肥胖且患有高血压的人群发生ADL残疾的风险逐渐增加(比值比[OR]=1.40,95%置信区间[CI]=1.05-1.89),体重过轻且无高血压的人群(OR=2.05,95%CI=1.29-3.25),以及体重过轻且患有高血压的人群(OR=2.14,95%CI=1.36-3.36)。对于IADL残疾,只有体重过轻且患有高血压的人群与之显著相关(OR=1.65,95%CI=1.23-2.21)。
低体重指数或极高体重指数,无论其代谢后果如何,都是老年人残疾的风险因素。单纯高血压与残疾无显著关联。此外,患有高血压会显著增加肥胖个体发生ADL残疾和体重过轻个体发生IADL残疾的风险。