Koyanagi Ai, Moneta Maria Victoria, Garin Noe, Olaya Beatriz, Ayuso-Mateos Jose Luis, Chatterji Somnath, Leonardi Matilde, Sainio Päivi, Galas Aleksander, Haro Josep Maria
Research and Development Unit, Parc Sanitari Sant Joan de Déu, Fundació Sant Joan de Déu, Sant Boi de Llobregat, Barcelona, Spain Instituto de Salud Carlos III, Centro de Investigación Biomédica en Red de Salud Mental, CIBERSAM, Madrid, Spain.
Research and Development Unit, Parc Sanitari Sant Joan de Déu, Fundació Sant Joan de Déu, Sant Boi de Llobregat, Barcelona, Spain Instituto de Salud Carlos III, Centro de Investigación Biomédica en Red de Salud Mental, CIBERSAM, Madrid, Spain Pharmacy Department, Hospital de la Santa Creu i Sant Pau, Institut d'Investigacions Biomédiques Sant Pau (IIB Sant Pau), Sant Antoni Maria Claret 167, 08025 Barcelona, Universitat Autónoma de Barcelona, Bellaterra 08193 (Cerdanyola del Vallés), Spain.
BMJ Open. 2015 Apr 2;5(4):e007313. doi: 10.1136/bmjopen-2014-007313.
The association between obesity and disability may differ between high-income and low-income/middle-income countries but there are no studies comparing this association between these settings. The aim of the study was to assess this association in nine countries using nationally-representative data from the Collaborative Research on Ageing in Europe (COURAGE) study and the WHO's Study on global AGEing and Adult Health (SAGE).
Population-based cross-sectional study
The survey was conducted in China, Finland, Ghana, India, Mexico, Poland, Russia, South Africa and Spain between 2007 and 2012.
42 116 individuals 50 years and older. The institutionalised and those with limited cognition were excluded.
Disability was defined as severe or extreme difficulty in conducting at least one of six types of basic activities of daily living (ADL).
The mean body mass index (BMI) ranged from 20.4 kg/m(2) in India to 30.7 kg/m(2) in South Africa. Compared to normal BMI (18.5-24.9 kg/m(2)), BMI≥35 kg/m(2) was associated with significantly higher odds for ADL disability in Finland (OR 4.64), Poland (OR 2.77), South Africa (OR 2.19) and Spain (OR 2.42). Interaction analysis showed that obese individuals in high-income countries were more likely to have ADL limitations than those in low-income or middle-income countries.
The higher odds for disability among obese individuals in high-income countries may imply longer life lived with disability due to factors such as the decline in cardiovascular disease mortality. In South Africa, this may have been due to the exceptionally high prevalence of class III obesity. These findings underscore the importance of obesity prevention to reduce the disability burden among older adults.
肥胖与残疾之间的关联在高收入国家和低收入/中等收入国家可能有所不同,但尚无研究比较这两类国家的这种关联。本研究旨在利用来自欧洲老龄化协作研究(COURAGE)和世界卫生组织全球老龄化与成人健康研究(SAGE)的全国代表性数据,评估九个国家中的这种关联。
基于人群的横断面研究
2007年至2012年期间在中国、芬兰、加纳、印度、墨西哥、波兰、俄罗斯、南非和西班牙开展了此项调查。
42116名50岁及以上的个体。排除了机构收容者和认知能力有限者。
残疾定义为在六项日常生活基本活动(ADL)中的至少一项上存在严重或极度困难。
平均体重指数(BMI)范围从印度的20.4kg/m²到南非的30.7kg/m²。与正常BMI(18.5 - 24.9kg/m²)相比,BMI≥35kg/m²与芬兰(OR 4.64)、波兰(OR 2.77)、南非(OR 2.19)和西班牙(OR 2.42)的ADL残疾几率显著更高相关。交互分析表明,高收入国家的肥胖个体比低收入或中等收入国家的肥胖个体更有可能存在ADL受限情况。
高收入国家肥胖个体的残疾几率较高,可能意味着由于心血管疾病死亡率下降等因素,残疾生存时间更长。在南非,这可能是由于III级肥胖的患病率异常高。这些发现强调了预防肥胖对于减轻老年人残疾负担的重要性。