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觉醒是否增强顶叶放大和去放大?

Does arousal enhance apical amplification and disamplification?

机构信息

Neurocure Cluster of Excellence,Department of Biology,Humboldt University,10117 Berlin,

Division of Psychology,School of Natural Sciences,University of Stirling,Stirling FK9 4LA,Scotland,United

出版信息

Behav Brain Sci. 2016 Jan;39:e215. doi: 10.1017/S0140525X15001867.

DOI:10.1017/S0140525X15001867
PMID:28347375
Abstract

We summarize evidence that input to the apical tufts of neocortical pyramidal cells modulates their response to basal input. Because this apical amplification and disamplification provide intracortical mechanisms for prioritization, Mather and colleagues' arguments suggest that their effects are enhanced by noradrenergic arousal. Though that is likely, it has not yet been adequately studied. Their article shows that it should be.

摘要

我们总结了证据,表明新皮层锥体神经元树突棘的输入调节了它们对基底输入的反应。由于这种树突棘的放大和去放大提供了皮层内的优先级机制,因此马瑟尔等人的论点表明,它们的作用是通过去甲肾上腺素的觉醒而增强的。虽然这很可能,但尚未得到充分研究。他们的文章表明,这应该是研究的重点。

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