Sardaneh Arwa A, Burke Rosemary, Ritchie Angus, McLachlan Andrew J, Lehnbom Elin C
Faculty of Pharmacy, University of Sydney, Sydney, Australia.
Pharmacy Department, Concord Repatriation General Hospital, Concord, Australia; Clinical Lead, Electronic Medication Management, Concord Repatriation General Hospital, Concord, Australia.
Int J Med Inform. 2017 May;101:41-49. doi: 10.1016/j.ijmedinf.2017.02.001. Epub 2017 Feb 8.
To investigate the impact of the introduction of an electronic medication management system on the proportion of patients with a recorded medication reconciliation on admission, the time from admission to when medication reconciliation was performed, and the characteristics of patients receiving this intervention pre-and post-implementation.
An electronic medication management system was implemented in an Australian hospital from May to July 2015. A retrospective observational study was conducted in three wards across two phases; pre- (August 2014) and post- (August 2015) implementation. The study sample included every second patient admitted to these wards.
A total of 370 patients were included, 179 pre- and 191 post-implementation. The proportion of recorded admission medication reconciliation significantly increased post-implementation in all study wards; coronary care unit (40 vs 68%, p=0.004), gastroenterology ward (39 vs 59%, p=0.015), and the neurology ward (19 vs 45%, p=0.002). The proportion of patients with recorded medication reconciliation within 24h of weekday admissions, or 48-72h of weekend admissions, increased from 47% pre- to 84% post-implementation. Admission medication reconciliation was recorded within a median of 1.0day for weekday admissions pre- and post-implementation (IQR 1.1 vs 0.2, respectively), and 3.5days (IQR 2.0) pre-implementation vs 1.5days (IQR 2.0) post-implementation for weekend admissions. Overall, across both phases pre-and post-implementation, admission medication reconciliation was recorded for patients who were significantly older (median 77 and 71 years, p<0.001), had a higher number of preadmission medications (median 6.5 and 5.0 medicines, p=0.001), and had a longer hospital stay (median 6.5 and 5.1days, p=0.003). A significantly higher proportion of patients with recorded medication reconciliation in the pre-implementation phase experienced polypharmacy (61%, p=0.002), hyperpolypharmacy (15%, p=0.001), and used a high-risk medication (44%, p=0.007).
Implementing an electronic medication management system facilitates the medication reconciliation process leading to more high risk patients receiving this service on admission to hospital and in a more timely manner. The impact of electronic medication reconciliation on patient safety and clinical outcomes remains unknown.
探讨引入电子药物管理系统对入院时进行药物重整记录的患者比例、从入院到进行药物重整的时间,以及实施干预前后接受该干预的患者特征的影响。
2015年5月至7月,澳大利亚一家医院实施了电子药物管理系统。在两个阶段对三个病房进行了回顾性观察研究;实施前(2014年8月)和实施后(2015年8月)。研究样本包括这些病房每第二位入院的患者。
共纳入370例患者,实施前179例,实施后191例。在所有研究病房中,实施后记录的入院药物重整比例显著增加;冠心病监护病房(40%对68%,p = 0.004)、胃肠病病房(39%对59%,p = 0.015)和神经科病房(19%对45%,p = 0.002)。工作日入院24小时内或周末入院48 - 72小时内有药物重整记录的患者比例从实施前的47%增加到实施后的84%。实施前后,工作日入院的药物重整记录中位数均为1.0天(四分位间距分别为1.1天和0.2天),周末入院实施前为3.5天(四分位间距2.0天),实施后为1.5天(四分位间距2.0天)。总体而言,在实施前后两个阶段,有药物重整记录的患者年龄显著更大(中位数分别为77岁和71岁,p < 0.001),入院前用药数量更多(中位数分别为6.5种和5.0种药物,p = 0.001),住院时间更长(中位数分别为6.5天和5.1天,p = 0.003)。实施前阶段有药物重整记录的患者中,多重用药(6l%,p = 0.002)、超多重用药(15%,p = 0.001)和使用高风险药物(44%,p = 0.007)的比例显著更高。
实施电子药物管理系统有助于药物重整过程,使更多高危患者入院时能更及时地接受这项服务。电子药物重整对患者安全和临床结局的影响尚不清楚。