Pivovarov A S, Izmest'ev V I
Zh Vyssh Nerv Deiat Im I P Pavlova. 1987 Nov-Dec;37(6):1099-109.
Blockade of dopamine receptors by haloperidol and serotonin receptors by lysergic acid diethylamide in turtle visual cortex, effectively changes the modifying effect of agonists of opioid mu-, delta-, kappa-, and sigma-receptors: morphine, D-Ala2, D-Leu5-enkephalin, bremazocine and SKF 10.047, on dynamics of habituation of orthodromic evoked potential. Muscarinic cholinergic blocker atropine disturbs the habituation modification by morphine and bremazocine. Conclusion is made, that modifying effects of opiate agonists on habituation are the result of interaction of activated opiate and transmitter receptors.
在龟的视皮层中,氟哌啶醇对多巴胺受体的阻断以及麦角酸二乙胺对5-羟色胺受体的阻断,有效地改变了阿片μ、δ、κ和σ受体激动剂(吗啡、D-丙氨酸2、D-亮氨酸5-脑啡肽、布马佐辛和SKF 10.047)对顺向诱发电位习惯化动力学的调节作用。毒蕈碱胆碱能阻滞剂阿托品扰乱了吗啡和布马佐辛对习惯化的调节。得出的结论是,阿片激动剂对习惯化的调节作用是活化的阿片受体与递质受体相互作用的结果。