Benjumea-Cuartas Vanessa, Eisermann Monika, Simonnet Hina, Hully Marie, Nabbout Rima, Desguerre Isabelle, Kaminska Anna
Department of Epilepsy, Neurocentro, Pereira, Colombia.
Department of Clinical Neurophysiology, Necker-Enfants Malades Hospital, APHP, Paris, France; INSERM U1129, Paris, France; Paris Descartes University, Sorbonne Paris Cité; CEA, Gif sur Yvette, France.
Epilepsy Behav Case Rep. 2017 Jan 18;7:42-44. doi: 10.1016/j.ebcr.2016.12.002. eCollection 2017.
Anti-NMDA receptor encephalitis is a treatable autoimmune disease characterized by cognitive, motor and psychiatric features that primarily affects young adults and children. We present a case of a 7-year-old boy with asymmetrical (mainly right hemibody) and abnormal polymorphic movements without concomitant scalpictal EEG changes but had background slowing predominating over the left hemisphere. This report illustrates previous descriptions of asymmetric presentation of abnormal movements in pediatric anti-NMDA receptor encephalitis and emphasizes the importance of video-EEG interpreted within the overall clinical context, to differentiate epileptic from non-epileptic abnormal movements in patients with autoimmune encephalitis.
抗N-甲基-D-天冬氨酸受体脑炎是一种可治疗的自身免疫性疾病，其特征为认知、运动和精神方面的症状，主要影响年轻人和儿童。我们报告一例7岁男孩，其有不对称（主要为右侧半身）且异常的多形性运动，头皮脑电图无相应改变，但背景活动减慢以左半球为主。本报告阐述了先前关于小儿抗N-甲基-D-天冬氨酸受体脑炎异常运动不对称表现的描述，并强调在整体临床背景下解读视频脑电图对于鉴别自身免疫性脑炎患者癫痫性与非癫痫性异常运动的重要性。
