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与卵巢癌及电压门控钾通道抗体相关的后部可逆性脑病综合征:一例报告

Posterior reversible encephalopathy syndrome (PRES) associated with ovarian cancer and voltage-gated potassium channel antibodies: A case report.

作者信息

Hadad Laura K, Billingsley Caroline C

机构信息

Department of Obstetrics and Gynecology, Division of Gynecology Oncology, University of Cincinnati, 231 Albert Sabin Way, Academic Health Center, PO Box 670526, Cincinnati, OH, 45267-0526, United States.

出版信息

Gynecol Oncol Rep. 2017 Mar 8;20:67-69. doi: 10.1016/j.gore.2017.02.010. eCollection 2017 May.

DOI:10.1016/j.gore.2017.02.010
PMID:28349115
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5357691/
Abstract

•We report a case of PRES in conjunction with high grade serous ovarian carcinoma•There is a documented association between chemotherapy agents and PRES•Paraneoplastic panel was positive for voltage-gated potassium channel antibodies•Paraneoplastic workup may be justified in cases with high suspicion of PRES.

摘要

•我们报告一例 PRES 合并高级别浆液性卵巢癌的病例

•化疗药物与 PRES 之间存在文献记载的关联

•副肿瘤检查中电压门控钾通道抗体呈阳性

•对于高度怀疑 PRES 的病例,进行副肿瘤检查可能是合理的。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/06d5/5357691/1136c5741350/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/06d5/5357691/1136c5741350/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/06d5/5357691/1136c5741350/gr1.jpg

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本文引用的文献

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Posterior reversible encephalopathy syndrome in cancer patients: a single institution retrospective study.癌症患者的后部可逆性脑病综合征:一项单中心回顾性研究。
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A Grave Outcome of Posterior Reversible Encephalopathy Syndrome in a Patient Receiving Avastin (Bevacizumab) for Metastatic High-Grade Serous Ovarian Cancer.
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Case Rep Oncol. 2015 Jul 16;8(2):290-4. doi: 10.1159/000435805. eCollection 2015 May-Aug.
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Posterior reversible encephalopathy syndrome: clinical and radiological manifestations, pathophysiology, and outstanding questions.后部可逆性脑病综合征:临床和影像学表现、病理生理学及待解决的问题。
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Autoimmun Rev. 2015 Sep;14(9):830-6. doi: 10.1016/j.autrev.2015.05.006. Epub 2015 May 18.
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Posterior reversible encephalopathy syndrome after bevacizumab therapy in a normotensive patient.贝伐单抗治疗后血压正常患者出现的后部可逆性脑病综合征。
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