Kraiem Tesnim, Barkaoui Abdelwahed, Chafra Moez, Hambli Ridha, Tavares João Manuel R S
a LR-11-ES19 Laboratoire de Mécanique Appliquée et Ingénierie (LR-MAI), Ecole Nationale d'Ingénieurs de Tunis , Université de Tunis El Manar , Tunis , Tunisie.
b Institut Préparatoire aux Etudes d'Ingénieurs d'El Manar , Université de Tunis El Manar , Tunis , Tunisie.
Comput Methods Biomech Biomed Engin. 2017 May;20(6):617-625. doi: 10.1080/10255842.2017.1280734. Epub 2017 Feb 9.
At the macroscopic scale, the bone mechanical behavior (fracture, elastic) depends mainly on its components' nature at the nanoscopic scale (collagen, mineral). Thus, an understanding of the mechanical behavior of the elementary components is demanded to understand the phenomena that can be observed at the macroscopic scale. In this article, a new numerical model based on finite element method is proposed in order to describe the mechanical behavior of a single Tropocollagen molecule. Furthermore, a parametric study with different geometric properties covering the molecular composition and the rate hydration influence is presented. The proposed model has been tested under tensile loading. While focusing on the entropic response, the geometric parameter variation effect on the mechanical behavior of Tropocollagen molecule has been revealed using the model. Using numerical and experimental testing, the obtained numerical simulation results seem to be acceptable, showing a good agreement with those found in literature.
在宏观尺度上，骨骼的力学行为（骨折、弹性）主要取决于其在纳米尺度上的组成部分的性质（胶原蛋白、矿物质）。因此，需要了解基本组成部分的力学行为，以便理解在宏观尺度上可以观察到的现象。在本文中，提出了一种基于有限元方法的新数值模型，以描述单个原胶原蛋白分子的力学行为。此外，还进行了参数研究，涵盖了分子组成和水化速率影响等不同几何特性。所提出的模型已在拉伸载荷下进行了测试。在关注熵响应的同时，利用该模型揭示了几何参数变化对原胶原蛋白分子力学行为的影响。通过数值和实验测试，所获得的数值模拟结果似乎是可以接受的，与文献中的结果显示出良好的一致性。
