Laliberte Benjamin, Kishk Omayma A
Department of Pharmacy Services, University of Maryland Medical Center, Baltimore, MD.
Pediatr Emerg Care. 2018 Dec;34(12):e226-e228. doi: 10.1097/PEC.0000000000001115.
Serotonin syndrome (SS) is a serious toxicity that manifests with symptoms such as tremor, hyperthermia, agitation, and altered mental status that may lead to seizures, coma, or death. Selective serotonin reuptake inhibitors may precipitate SS, particularly in combination with other drugs that possess serotonergic activity. We present a case of SS in a 14-month-old after an ingestion of the selective serotonin reuptake inhibitor vilazodone.
血清素综合征(SS)是一种严重的毒性反应,表现为震颤、高热、激动以及精神状态改变等症状,可能导致癫痫发作、昏迷或死亡。选择性血清素再摄取抑制剂可能引发血清素综合征,尤其是与其他具有血清素能活性的药物合用时。我们报告一例14个月大的幼儿在摄入选择性血清素再摄取抑制剂维拉唑酮后发生血清素综合征的病例。