ESH Centre of Excellence for Hypertension, 1st Cardiology Department, "Hippokration" Hospital, National and Kapodistrian University of Athens, Medical School, Athens, Greece.
ESH Centre of Excellence for Hypertension, Cardiology Department, "KAT" General Hospital of Attica, Athens, Greece.
Hellenic J Cardiol. 2017 Jul-Aug;58(4):261-266. doi: 10.1016/j.hjc.2017.03.005. Epub 2017 Mar 27.
Arterial hypertension and aortic valve stenosis are common disorders and frequently present as concomitant diseases, especially in elderly patients. The impact of hypertension on heart haemodynamics is substantial, thus affecting the clinical presentation of any coexisting valvulopathy, especially of aortic stenosis. However, the interaction between these 2 entities is not thoroughly discussed in the European or/and American guidelines on the management of hypertension or/and valvular heart disease. The present review summarizes all available evidence on the potential interplay between hypertension and aortic valve stenosis, aiming to help physicians understand the pathophysiology and select the best diagnostic and therapeutic strategies (medical or/and interventional) for better management of these high-risk patients, taking into account the impact on outcome as well as the risk-benefit-ratio.
动脉高血压和主动脉瓣狭窄是常见疾病，常同时存在，尤其是在老年患者中。高血压对心脏血液动力学的影响很大，因此会影响任何共存瓣膜病的临床表现，尤其是主动脉瓣狭窄。然而，在欧洲或/和美国关于高血压或/和心脏瓣膜病管理的指南中，并没有深入讨论这两种疾病之间的相互作用。本综述总结了高血压和主动脉瓣狭窄之间潜在相互作用的所有现有证据，旨在帮助医生了解病理生理学，并选择最佳的诊断和治疗策略（药物或/和介入），以更好地管理这些高危患者，同时考虑对预后的影响以及风险效益比。
