Labarga Alberto, Beloqui Izaskun, Martin Angel G
Department of Computer Science and Artificial Intelligence, University of Granada, Gardana, Spain.
StemTek Therapeutics, Kabi612, Parque Tecnologico de Bizkaia, Astondo Bidea s/n, 48160, Derio, Spain.
Methods Mol Biol. 2017;1590:29-39. doi: 10.1007/978-1-4939-6921-0_4.
The collection and storage of human tissue samples has been undertaken in medicine for centuries; however, biobanking has only recently become a dedicated activity. The technological developments that have allowed the procurement and long-term storage of viable human cells ex vivo, and to obtain relevant scientific information, including genetic information, provide tremendous possibilities for advancing biomedical research. At the same time, these possibilities have raised complex information management issues regarding samples, processing, donor information, traceability, and use of the sample. This chapter considers the requirements for managing information within biobanks, critical to their operation. Special consideration is given to Laboratory Information Managing Systems (LIMS) as a tool for comprehensive access and storage of information.
几个世纪以来,医学领域一直在进行人体组织样本的采集和存储;然而,生物样本库直到最近才成为一项专门的活动。技术的发展使得在体外获取并长期存储有活力的人体细胞,并获得包括基因信息在内的相关科学信息成为可能,这为推进生物医学研究提供了巨大的可能性。与此同时,这些可能性引发了有关样本、处理、捐赠者信息、可追溯性以及样本使用等方面复杂的信息管理问题。本章将探讨生物样本库信息管理的要求,这对其运作至关重要。特别关注实验室信息管理系统(LIMS)作为全面获取和存储信息的工具。