Laboratory for Clinical Neuroscience,Centro de Tecnología Biomédica,Universidad Politecnica de Madrid,Pozuelo de Alarcón,Madrid 28223,
Behav Brain Sci. 2016 Jan;39:e224. doi: 10.1017/S0140525X15001958.
Emotional events can either impair or enhance memory for immediately preceding items. The GANE model explains this bidirectional effect as a glutamate "priority" signal that modulates noradrenaline release depending on arousal state. We argue for an alternative explanation: that priority itself evokes phasic noradrenaline release. Thus, contrasting E-1 memory effects are explained by a mechanism based on the Bienenstock-Cooper-Munro theory.
情绪事件会损害或增强对紧接着的项目的记忆。GANE 模型将这种双向效应解释为一种谷氨酸“优先级”信号，根据唤醒状态调节去甲肾上腺素的释放。我们提出了另一种解释：优先级本身会引发阵发性去甲肾上腺素释放。因此，基于 Bienenstock-Cooper-Munro 理论的机制可以解释 E-1 记忆效应的差异。
