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成釉细胞纤维瘤或纤维肉瘤:口腔外科医生的两难困境。

Ameloblastic fibroma or fibrosarcoma: A dilemma of oral surgeon.

作者信息

Verma Nitin

机构信息

Department of Oral and Maxillofacial Surgery, Government Dental College and Hospital, Amritsar, Punjab, India.

出版信息

Natl J Maxillofac Surg. 2016 Jul-Dec;7(2):191-193. doi: 10.4103/0975-5950.201359.

Abstract

Ameloblastic fibroma (AF) is an uncommon true mixed odontogenic tumor, with a relative frequency between 1.5% and 4.5% of all odontogenic tumors. It may behave either as a true neoplasm or as a hamartomatous proliferation of odontogenic epithelium of the enamel organ and odontogenic mesenchyme of the primitive dental pulp. Frequently diagnosed between the first and second decades of life with 75% of cases was diagnosed before the age of 20 and present with a well-defined unilocular or multilocular radiolucencies. A conservative approach, enucleation with curettage, and long-term follow-up are absolutely necessary for any recurrence or change to fibrosarcoma. We report a case of AF in a 10-year-old male patient who presented with a chief complaint of swelling in the right mandibular posterior region. Enucleation and curettage were done under general anesthesia, followed by immunohistochemical markers (Ki-67, Mib-1) to assess the sarcomatous changes and aggressiveness of the tumor.

摘要

成釉细胞纤维瘤(AF)是一种罕见的真正的混合性牙源性肿瘤,在所有牙源性肿瘤中的相对发生率为1.5%至4.5%。它既可以表现为真正的肿瘤,也可以表现为牙釉质器官的牙源性上皮和原始牙髓的牙源性间充质的错构瘤样增生。常在生命的第一个和第二个十年间被诊断出来,75%的病例在20岁之前被诊断,表现为边界清晰的单房或多房透射区。对于任何复发或向纤维肉瘤的转变,保守的方法、刮除术摘除以及长期随访是绝对必要的。我们报告一例10岁男性患者的成釉细胞纤维瘤病例,其主要症状为右下颌后区肿胀。在全身麻醉下进行了摘除和刮除术,随后进行免疫组化标记物(Ki-67、Mib-1)检测以评估肿瘤的肉瘤样改变和侵袭性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/aec1/5357928/81486ba91d56/NJMS-7-191-g001.jpg

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