Department of Oral and Maxillofacial Pathology, Kantipur Dental College Teaching Hospital, Dhapasi, Kathmandu, Nepal.
Kathmandu Univ Med J (KUMJ). 2023 Apr-Jun;21(82):230-234.
Ameloblastic fibroma (AF) is a benign mixed epithelial and mesenchymal odontogenic tumor. This was previously grouped in odontogenic tumor showing odontogenic epithelium with odontogenic ectomesenchyme, with or without hard tissue formation. This report describes a case of ameloblastic fibroma in a 37-yearold male who came with the complain of swelling in the left side of lower jaw since one year. Enucleation of the mass followed by reconstruction was done six years back. However, after two years of initial treatment; radiographic findings suggested recurrence. Histopathological examination confirmed the diagnosis of ameloblastic fibroma. Patient had no clinical and radiographic evidence of recurrence in three and six months' follow-up. Because of the higher proliferative capacity and malignant degree of the mesenchymal component in the recurrent neoplasm, sarcomatous transformation may occur. Hence, a long term clinical and radiographical follow-up is essential due to its transformation into ameloblastic fibrosarcoma.
成釉细胞瘤(AF)是一种良性的混合上皮和间叶性牙源性肿瘤。该肿瘤以前被归类为牙源性肿瘤,表现为具有牙源性外胚间充质的牙源性上皮,伴有或不伴有硬组织形成。本报告描述了一例 37 岁男性的成釉细胞瘤病例,该患者因左下颌肿胀一年就诊。六年前进行了肿块的剜除术和重建术。然而,在初始治疗两年后;放射学检查结果提示复发。组织病理学检查证实了成釉细胞瘤的诊断。在三到六个月的随访中,患者均无临床和放射影像学复发的证据。由于复发性肿瘤中间充质成分的增殖能力和恶性程度较高,可能会发生肉瘤样转化。因此,由于其可能转化为成釉纤维肉瘤,因此需要进行长期的临床和放射影像学随访。