慢性镰状细胞性腿部溃疡中的局部用抗生素
Topical antibiotics in chronic sickle cell leg ulcers.
作者信息
Baum K F, MacFarlane D E, Maude G H, Serjeant G R
机构信息
Medical Research Council Laboratories, University of the West Indies, Kingston, Jamaica.
出版信息
Trans R Soc Trop Med Hyg. 1987;81(5):847-9. doi: 10.1016/0035-9203(87)90049-6.
A randomized, controlled, trial of a topical antibiotic preparation (neomycin, bacitracin, and polymyxin B) was performed in 30 patients with homozygous sickle cell (SS) disease and chronic leg ulceration. Over a period of 8 weeks, the reduction in ulcer size was significantly (P less than 0.05) greater in the treatment group than in the control group. The results suggest that these topical antibiotics may contribute to the therapy of chronic leg ulceration associated with sickle cell disease.
对30例纯合子镰状细胞（SS）病合并慢性腿部溃疡的患者进行了一项局部用抗生素制剂（新霉素、杆菌肽和多粘菌素B）的随机对照试验。在8周的时间里，治疗组溃疡面积的缩小幅度显著（P<0.05）大于对照组。结果表明，这些局部用抗生素可能有助于镰状细胞病相关慢性腿部溃疡的治疗。
Zotero 插件