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The lure of the lipids: how defensins exploit membrane phospholipids to induce cytolysis in target cells.

作者信息

Baxter Amy A, Poon Ivan Kh, Hulett Mark D

机构信息

Department of Biochemistry and Genetics, La Trobe Institute for Molecular Science, La Trobe University, Melbourne 3086, Victoria, Australia.

出版信息

Cell Death Dis. 2017 Mar 30;8(3):e2712. doi: 10.1038/cddis.2017.69.

DOI:10.1038/cddis.2017.69
PMID:28358378
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5386563/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5377/5386563/4dd9ddffa616/cddis201769f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5377/5386563/4dd9ddffa616/cddis201769f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5377/5386563/4dd9ddffa616/cddis201769f1.jpg

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Cell Death Discov. 2017 Jan 23;3:16102. doi: 10.1038/cddiscovery.2016.102. eCollection 2017.
2
Binding of phosphatidic acid by NsD7 mediates the formation of helical defensin-lipid oligomeric assemblies and membrane permeabilization.NsD7对磷脂酸的结合介导了螺旋防御素-脂质寡聚体组装体的形成及膜通透化。
Proc Natl Acad Sci U S A. 2016 Oct 4;113(40):11202-11207. doi: 10.1073/pnas.1607855113. Epub 2016 Sep 19.
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Convergent evolution of defensin sequence, structure and function.
在翼手目中抗菌肽的进化。
Front Immunol. 2023 Sep 26;14:1250229. doi: 10.3389/fimmu.2023.1250229. eCollection 2023.
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Diversity of Antimicrobial Peptides in Silkworm.家蚕抗菌肽的多样性
Life (Basel). 2023 May 11;13(5):1161. doi: 10.3390/life13051161.
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Nat Commun. 2023 Mar 1;14(1):1170. doi: 10.1038/s41467-023-36280-y.
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J Mol Model. 2019 Aug 29;25(9):281. doi: 10.1007/s00894-019-4163-8.
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Sci Adv. 2018 Jul 25;4(7):eaat0979. doi: 10.1126/sciadv.aat0979. eCollection 2018 Jul.
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