Rad51 inhibition sensitizes breast cancer stem cells to PARP inhibitor in triple-negative breast cancer.
作者信息
Wang Dong, Du Ruikai, Liu Suling
机构信息
The CAS Key Laboratory of Innate Immunity and Chronic Disease, Hefei National Laboratory for Physical Sciences at the Microscale, School of Life Science and Medical Center, University of Science & Technology of China, Hefei, 230027, Anhui, P. R. China.
Key Laboratory of Breast Cancer in Shanghai, Cancer Institute, Department of Breast Surgery, Fudan University Shanghai Cancer Center, Shanghai, 200032, P. R. China.
出版信息
Chin J Cancer. 2017 Mar 30;36(1):37. doi: 10.1186/s40880-017-0204-9.
Abstract
摘要
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本文引用的文献
1
RAD51 Mediates Resistance of Cancer Stem Cells to PARP Inhibition in Triple-Negative Breast Cancer.RAD51 介导三阴性乳腺癌肿瘤干细胞对 PARP 抑制剂的耐药性。
Clin Cancer Res. 2017 Jan 15;23(2):514-522. doi: 10.1158/1078-0432.CCR-15-1348. Epub 2016 Dec 29.
2
ERCC1 and BRAC1 mRNA expression levels in the primary tumor could predict the effectiveness of the second-line cisplatin-based chemotherapy in pretreated patients with metastatic non-small cell lung cancer.原发肿瘤中 ERCC1 和 BRAC1 mRNA 表达水平可预测经治转移性非小细胞肺癌患者二线含铂化疗的疗效。
J Thorac Oncol. 2012 Apr;7(4):663-71. doi: 10.1097/JTO.0b013e318244bdd4.
3
PARP inhibitors: its role in treatment of cancer.聚（ADP-核糖）聚合酶抑制剂：其在癌症治疗中的作用。
Chin J Cancer. 2011 Jul;30(7):463-71. doi: 10.5732/cjc.011.10111.
4
Oral poly(ADP-ribose) polymerase inhibitor olaparib in patients with BRCA1 or BRCA2 mutations and recurrent ovarian cancer: a proof-of-concept trial.奥拉帕利在携带 BRCA1 或 BRCA2 突变的复发性卵巢癌患者中的疗效：一项概念验证试验。
Lancet. 2010 Jul 24;376(9737):245-51. doi: 10.1016/S0140-6736(10)60893-8. Epub 2010 Jul 6.
5
ELDA: extreme limiting dilution analysis for comparing depleted and enriched populations in stem cell and other assays.ELDA：用于在干细胞及其他检测中比较耗尽和富集群体的极限稀释分析。
J Immunol Methods. 2009 Aug 15;347(1-2):70-8. doi: 10.1016/j.jim.2009.06.008. Epub 2009 Jun 28.
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Breast cancer cell lines contain functional cancer stem cells with metastatic capacity and a distinct molecular signature.乳腺癌细胞系包含具有转移能力和独特分子特征的功能性癌症干细胞。
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The Rad51/RadA N-terminal domain activates nucleoprotein filament ATPase activity.Rad51/RadA的N端结构域激活核蛋白丝ATP酶活性。
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Cancer susceptibility and the functions of BRCA1 and BRCA2.癌症易感性以及BRCA1和BRCA2的功能。
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