Michailidou M, Nfonsam V N
Department of Surgery, Division of Surgical Oncology, University of Arizona, Tucson, AZ, USA.
Department of Surgery, Division of Surgical Oncology, University of Arizona, Tucson, AZ, USA.
Am J Surg. 2018 Jan;215(1):78-81. doi: 10.1016/j.amjsurg.2017.02.016. Epub 2017 Mar 14.
Anemia is the most common extraintestinal manifestation in patients with inflammatory bowel disease (IBD), and has been linked to severity of the disease. The aim of the study was to assess the impact of anemia on postoperative outcomes in patients with IBD.
We retrospectively reviewed patients with IBD from the NSQIP database over an 8-year period. Patients were grouped based on the presence of anemia. The impact of anemia on postoperative morbidity, mortality and length of stay was assessed.
A total of 15,761 patients met our criteria. Half of the patients were anemic upon presentation. Anemic patients were more likely to have a history of steroid use, present with sepsis and require an emergency operation. In multivariate analysis, anemia was a significant predictor of overall morbidity, serious morbidity and increased length of stay.
Anemic patients with IBD present more often with sepsis and require emergency surgery compared to their peers. In addition, anemia serves as an independent predictor of overall complications, serious morbidity and increased length of stay following abdominal operations.
贫血是炎症性肠病（IBD）患者最常见的肠外表现，且与疾病严重程度相关。本研究旨在评估贫血对IBD患者术后结局的影响。
我们回顾性分析了NSQIP数据库中8年间的IBD患者。根据是否存在贫血对患者进行分组。评估贫血对术后发病率、死亡率和住院时间的影响。
共有15761例患者符合我们的标准。半数患者就诊时存在贫血。贫血患者更有可能有使用类固醇的病史，出现败血症并需要急诊手术。在多变量分析中，贫血是总体发病率、严重发病率和住院时间延长的显著预测因素。
与非贫血的IBD患者相比，贫血患者更常出现败血症并需要急诊手术。此外，贫血是腹部手术后总体并发症、严重发病率和住院时间延长的独立预测因素。
