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探讨能量平衡相关行为在欧洲成年人睡眠时长与肥胖之间的关联中的中介作用。SPOTLIGHT 项目。

Exploring the mediating role of energy balance-related behaviours in the association between sleep duration and obesity in European adults. The SPOTLIGHT project.

机构信息

Department of Epidemiology and Biostatistics, Amsterdam Public Health Research Institute, VU University Medical Center, Amsterdam, The Netherlands.

Department of Epidemiology and Biostatistics, Amsterdam Public Health Research Institute, VU University Medical Center, Amsterdam, The Netherlands.

出版信息

Prev Med. 2017 Jul;100:25-32. doi: 10.1016/j.ypmed.2017.03.021. Epub 2017 Mar 28.

Abstract

Sleep restriction is a risk factor for weight gain and obesity. Few studies have formally investigated the mediating role of energy balance-related behaviours in the sleep - obesity association. The aim of this study was to explore the mediating role of physical activity, sedentary behaviours and dietary habits in the association of sleep duration with obesity in adults in five European urban regions. Data on self-reported sleep duration, energy balance-related behaviours, height and weight and other covariates were collected between February and September 2014 from participants to the SPOTLIGHT survey (N=5900, mean age 52years). Participants were recruited from 60 urban neighbourhoods in Belgium, France, Hungary, the Netherlands and the United Kingdom. Multilevel logistic regression analyses were used to assess the associations of sleep duration, energy balance-related behaviours and obesity and mediating effects were calculated using MacKinnon's product-of-coefficients method. Results indicated that a 1h increase in sleeping time was associated with a 14% lower likelihood of being obese (OR=0.86, 95%CI=0.80; 0.93). Only work-related sedentary behaviour was identified as a statistically significant mediator in the association between sleep duration and obesity for the total sample, and youngest and oldest age group. We did not find evidence for a mediating role of dietary habits and physical activities.

摘要

睡眠限制是体重增加和肥胖的一个风险因素。很少有研究正式调查能量平衡相关行为在睡眠 - 肥胖关联中的中介作用。本研究旨在探讨在五个欧洲城市地区,成年人的睡眠持续时间与肥胖之间的关联中,身体活动、久坐行为和饮食习惯的中介作用。

2014 年 2 月至 9 月,在 SPOTLIGHT 调查中(N=5900,平均年龄 52 岁),从参与者那里收集了自我报告的睡眠持续时间、能量平衡相关行为、身高和体重以及其他协变量的数据。参与者来自比利时、法国、匈牙利、荷兰和英国的 60 个城市社区。

使用多层次逻辑回归分析评估睡眠持续时间、能量平衡相关行为和肥胖之间的关联,并使用 MacKinnon 的乘积系数法计算中介效应。结果表明,睡眠时间增加 1 小时,肥胖的可能性降低 14%(OR=0.86,95%CI=0.80;0.93)。

仅在总样本以及最年轻和最年长的年龄组中,与睡眠持续时间和肥胖相关的工作相关久坐行为被确定为统计学上显著的中介因素。我们没有发现饮食习惯和身体活动的中介作用的证据。

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