Nair Vidya, Sharma Rahul Kumar, Khanna Arjun, Talwar Deepak
Metro Centre for Respiratory Diseases, Metro Multispecialty Hospital, Sector 11, Noida, Uttar Pradesh, India.
Lung India. 2017 Mar-Apr;34(2):179-181. doi: 10.4103/0970-2113.201320.
Pulmonary mucormycosis is an opportunistic fungal infection in immunocompromised individuals. It is difficult to diagnose as it requires tissue biopsy, and generally these patients are unfit to undergo invasive lung biopsies. We describe a novel technique in a case with uncontrolled diabetes mellitus with nonresolving pulmonary cavitary disease where convex probe endobronchial ultrasound (EBUS)-guided aspiration of lung cavity wall showed classical histopathological picture establishing the diagnosis of mucorale infection. EBUS being real-time, minimally invasive technique with minimal risk of complications, led to early diagnosis, and prompt treatment. This appears to be a novel diagnostic modality in pulmonary mucormycosis with minimal complications as compared with other biopsy methods with very high complication risk.
肺毛霉病是免疫功能低下个体的一种机会性真菌感染。由于其诊断需要组织活检,而这些患者通常不适合接受侵入性肺活检,所以诊断困难。我们描述了一种新技术,应用于一名患有未控制的糖尿病且肺部空洞性疾病未缓解的患者,凸阵探头支气管内超声(EBUS)引导下对肺空洞壁进行穿刺抽吸,显示出典型的组织病理学图像,从而确诊为毛霉感染。EBUS是一种实时、微创技术,并发症风险极小,可实现早期诊断和及时治疗。与其他具有很高并发症风险的活检方法相比,这似乎是一种诊断肺毛霉病的新方法,并发症极少。