Auer Ronald, Riehl John
King's Daughters' Hospital, USA.
Baptist Health Care and the Andrews Institute, 1717 North E. Street, Suite 208, Pensacola, FL 32501, USA.
J Clin Orthop Trauma. 2017 Jan-Mar;8(1):38-44. doi: 10.1016/j.jcot.2017.01.007. Epub 2017 Jan 27.
Controversy exists regarding the routine use of chemical prophylaxis in isolated lower extremity fractures. The incidence of VTE in specific fracture locations in the lower extremity is largely unknown, and represents key information necessary to determine the need for prophylaxis. A large cross-sectional study using the National Trauma Databank was performed evaluating for the incidence and risk factors of VTE in isolated tibia fractures. The overall incidence of DVT and PE are extremely low in cases of isolated tibia fractures, which brings into doubt a role for routine use of chemical prophylaxis for these fractures.
关于在单纯下肢骨折中常规使用化学预防措施存在争议。下肢特定骨折部位静脉血栓栓塞(VTE)的发生率很大程度上未知,而这是确定是否需要预防的关键信息。利用国家创伤数据库进行了一项大型横断面研究,评估单纯胫骨骨折中VTE的发生率和危险因素。单纯胫骨骨折病例中深静脉血栓形成(DVT)和肺栓塞(PE)的总体发生率极低,这使得常规使用化学预防措施对这些骨折的作用受到质疑。