Kocasoy Orhan Elif, Atmaca M Mert, Atmaca Melek, Hanağasi Haşmet A
İstanbul University İstanbul Faculty of Medicine, Department of Neurology, İstanbul, Turkey.
Bakırköy Mental Health and Neurology Hospital, Clinic of the 3 Neurology, İstanbul, Turkey.
Noro Psikiyatr Ars. 2013 Dec;50(4):375-378. doi: 10.4274/npa.y6468. Epub 2013 Dec 1.
Chorea-ballismus which is a rare complication of nonketotic hyperglycemia may be the first symptom of type 2 diabetes mellitus. In this paper, we present two patients, who had involuntary movements and were diagnosed as having ballismus-chorea associated with nonketotic hyperglycemia. While one of the patients was not diagnosed with diabetes mellitus, the other one did not administer insulin therapy for a long time which was prescribed. The patients were investigated by cranial imaging and biochemical tests. The symptoms improved in one of them within hours, however, it took days to improve for the other one. This clinical situation, which is thought to be caused by hyperglycemia, cerebral ischemia and failure of gamma-aminobutyric acid (GABA) and which probably improves with regulation of blood glucose levels, should be kept in mind by emergency physicians, because it can be the first presentation of type 2 diabetes mellitus.
舞蹈样手足徐动症是非酮症高血糖症的一种罕见并发症，可能是2型糖尿病的首发症状。在本文中，我们介绍了两名患者，他们出现了不自主运动，被诊断为与非酮症高血糖症相关的手足徐动-舞蹈症。其中一名患者未被诊断出患有糖尿病，另一名患者长期未按医嘱进行胰岛素治疗。对这两名患者进行了头颅影像学和生化检查。其中一名患者的症状在数小时内得到改善，而另一名患者则需要数天时间才能改善。这种临床情况被认为是由高血糖、脑缺血以及γ-氨基丁酸（GABA）功能障碍引起的，可能随着血糖水平的调节而改善，急诊医生应牢记这一点，因为它可能是2型糖尿病的首次表现。
