Kocatürk Bülent Kenan, Eşsizoğlu Altan, Aksaray Gökay, Akarsu Ferdane Özlem, Musmul Ahmet
Clinic of Psychiatry, Yunus Emre State Hospital, Eskişehir, Turkey.
Department of Psychiatry, Eskişehir Osmangazi University Faculty of Medicine, Eskişehir, Turkey.
Noro Psikiyatr Ars. 2015 Jun;52(2):169-173. doi: 10.5152/npa.2015.7506. Epub 2015 Jun 1.
The aim of this study was to compare schizophrenic patients with and without a suicide attempt history in terms of sociodemographic and clinical features and cognitive functions and to determine the predictive factors for suicide attempt history.
In this study, we assessed and compared 70 patients with schizophrenia, 27 patients with a suicide attempt history, and 43 patients without a suicide attempt history. The cognitive functions of patients were assessed by the Stroop test, Wisconsin Card Sorting Test (WCST), and Rey Auditory Verbal Learning Test. In order to evaluate clinical symptoms, the Positive and Negative Syndrome Scale (PANSS) and Calgary Depression Scale for Schizophrenia (CDSS) were used.
In this study, the number of hospitalizations, PANSS general psychopathology subscale score, CDSS total score, suicide item score, and WCST total number of responses (WCST1) were significantly higher among the patients with a suicide attempt history. The WCST1 and CDSS total scores were predicted using the suicide attempt history.
Revealing the factors related to suicidal behavior in patients with schizophrenia contributes to the prevention of suicide. Studies with long-term follow-up and with a larger sample group are required for the investigation of relationship suicide, cognitive impairment, which is one of the core symptoms of schizophrenia, and depression.
本研究旨在比较有和没有自杀未遂史的精神分裂症患者在社会人口学、临床特征和认知功能方面的差异，并确定自杀未遂史的预测因素。
在本研究中，我们评估并比较了70例精神分裂症患者，其中27例有自杀未遂史，43例无自杀未遂史。通过斯特鲁普测验、威斯康星卡片分类测验（WCST）和雷伊听觉词语学习测验评估患者的认知功能。为了评估临床症状，使用了阳性和阴性症状量表（PANSS）和精神分裂症卡尔加里抑郁量表（CDSS）。
在本研究中，有自杀未遂史的患者住院次数、PANSS一般精神病理学分量表得分、CDSS总分、自杀项目得分以及WCST总反应次数（WCST1）显著更高。使用自杀未遂史可预测WCST1和CDSS总分。
揭示精神分裂症患者自杀行为的相关因素有助于预防自杀。需要进行长期随访和更大样本量的研究来调查自杀、认知障碍（精神分裂症的核心症状之一）和抑郁之间的关系。
