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长效注射用利培酮在一名11岁双相情感障碍儿童中的应用

Long-acting Injectable Risperidone Use in an 11-Years-Old Bipolar Child.

作者信息

Karakoç Demirkaya Sevcan, Zoroğlu Süleyman Salih

机构信息

Department of Child and Adolescent Psychiatry, Adnan Menderes University School of Medicine, Aydın, Turkey.

Department of Child and Adolescent Psychiatry, İstanbul University İstanbul School of Medicine, İstanbul, Turkey.

出版信息

Noro Psikiyatr Ars. 2016 Dec;53(4):361-363. doi: 10.5152/npa.2015.10150. Epub 2016 Apr 15.

Abstract

Early-onset bipolar disorder is difficult for child psychiatrists in terms of both diagnosis and treatment. The proper diagnostic evaluation is negatively impacted by the atypical clinical manifestation and rapid cycling pattern of the disease, together with common comorbidity with attention-deficit hyperactivity disorder and anxiety disorder. In addition to poor insight, nonadherence to treatment, poor family coping skills, and insufficient child psychiatric inpatient units make clinicians unsuccessful in following up and treating such patients. Risperidone is a commonly used atypical antipsychotic it has been approved for the treatment of manic and mixed episodes of bipolar disorder even in 10-17-year-old patients, and it is commonly used. It has a long-acting injectable formulation. Studies on its long-acting form in younger children are limited. In this case presentation, the diagnostic procedure in an 11-year old child with bipolar disorder will be presented. Long-acting injectable risperidone use in the case of nonadherence to treatment and observed side effects will be discussed.

摘要

早发性双相情感障碍对于儿童精神科医生来说,在诊断和治疗方面都颇具难度。该疾病非典型的临床表现、快速循环模式,以及与注意力缺陷多动障碍和焦虑症的常见共病情况,对正确的诊断评估产生了负面影响。除了洞察力差、不依从治疗、家庭应对能力差之外,儿童精神科住院单元不足也使得临床医生在随访和治疗这类患者时难以取得成效。利培酮是一种常用的非典型抗精神病药物,它已被批准用于治疗双相情感障碍的躁狂和混合发作,甚至适用于10至17岁的患者,且应用广泛。它有一种长效注射剂型。针对年幼儿童使用其长效剂型的研究有限。在本病例报告中,将呈现一名11岁双相情感障碍患儿的诊断过程。还将讨论在不依从治疗的情况下使用长效注射用利培酮以及观察到的副作用。

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