Drannik G N, Seniuk O F, Sakalo V S, Persidskiĭ Iu V, Poludnenko L Iu
Eksp Onkol. 1988;10(1):30-4.
The level of activity in natural killer cells (mononuclears) of peripheral blood relative to 51C-labelled K-562 cells is found to be significantly lower in patients with germinative testicle tumours than in donors. At the same time neither mononuclears of the peripheral blood nor those isolated from the tumour tissue practically lyse tumour tissue cells. The higher activity of natural killer cells relative to K-562 cells corresponds to the higher immunocellular infiltration of the tissue from nonseminomatous tumours.
与51C标记的K-562细胞相比,精原细胞瘤患者外周血中自然杀伤细胞(单核细胞)的活性水平显著低于供体。同时,外周血单核细胞以及从肿瘤组织中分离出的单核细胞实际上都不会裂解肿瘤组织细胞。相对于K-562细胞,自然杀伤细胞的较高活性对应于非精原细胞瘤组织中较高的免疫细胞浸润。