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碱中毒与大鼠肾脏氨的排泄

Alkalosis and renal excretion of ammonia by rat kidney.

作者信息

Solomon S

机构信息

University of New Mexico School of Medicine, Albuquerque 87131.

出版信息

Experientia. 1988 May 15;44(5):453-5. doi: 10.1007/BF01940545.

Abstract

Upon sulfate administration, UpH falls more in alkalotic rats than in controls. Alkalosis can lead to a reduction in UNH3 V at highly acidic urine. The significance of this process is doubtful at UpH ranging from about 6 to 7. At lower UpH less NH3 would be excreted, thereby less H+ would be trapped in urine and some acid would be conserved.

摘要

给予硫酸盐后,碱中毒大鼠的尿液pH值下降幅度比对照组更大。碱中毒可导致在高酸性尿液中尿氨(UNH3)排泄量减少。在尿液pH值约为6至7的范围内,这一过程的意义尚不确定。在较低的尿液pH值下,氨的排泄量会减少,从而尿液中捕获的氢离子也会减少,部分酸得以保留。

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