• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

食用水煮面包果树(非洲面包树)种子对链脲佐菌素诱导的糖尿病大鼠的高血糖症并无改善作用:对正常血糖大鼠口服葡萄糖耐量的影响。

Dietary intake of boiled breadfruit (Treculia africana) seeds did not improve hyperglycemia in streptozotocin induced diabetic rats: Effect on the oral glucose tolerance of normoglycemic rats.

作者信息

Eleazu Chinedum, Ezekwibe Ifeoma, Egbe Mary, Saidu Sanni, Eleazu Kate, Egedigwe Chima

机构信息

Federal University Ndufu-Alike, Ikwo, Nigeria.

Michael Okpara University of Agriculture, Umudike, Nigeria.

出版信息

Acta Sci Pol Technol Aliment. 2017 Jan-Mar;16(1):93-99. doi: 10.17306/J.AFS.2017.0460.

DOI:10.17306/J.AFS.2017.0460
PMID:28362476
Abstract

BACKGROUND

Although African breadfruit (Treculia africana) is said to be useful in the dietary management of diabetes, the effect of cooking on its glycemic index has not been reported. Hence this study has investi- gated the effect of a dietary intake of boiled breadfruit on the serum glucose, glucose tolerance, body weights and relative organ weights of streptozotocin (STZ) induced diabetic rats.

METHODS

Twenty albino rats were used and were divided into four groups of five rats. Groups 1 (normal control) and 2 (diabetic control) received standard rat pellets while groups 3 (diabetic-test group) and 4 (non-diabetic) rats received breadfruit.

RESULTS

The blood glucose of the normoglycemic rats fed standard rat feeds peaked at 30 min (149.75 ±11.12 mg/dl) following oral glucose loading (3 g/kg) but reduced to 85.25 ±21.05 mg/dl after another 90 min, while the blood glucose of the normoglycemic rats fed breadfruit peaked at 30 min (146.25 ±15.22 mg/dl) follow- ing oral glucose loading, but elevated (130.75 ±36.69 mg/dl) after another 90 min. There was significant elevation (P < 0.05) of the serum glucose, relative liver weight (RLW) and relative kidney weight (RKW) but a significant decrease in the body weights of the diabetic control compared with the normal control; no sig- nificant difference (P > 0.05) in the serum glucose, body weights, RLW and RKW of the test group compared with the diabetic control, and no significant differences (P > 0.05) in the serum glucose, body weights, RLW and RKW of the normal rats fed the breadfruit diet compared to the normal control.

CONCLUSIONS

The study showed that the traditional method of cooking African breadfruit negatively affects its hypoglycemic property.

摘要

背景

尽管非洲面包果(Treculia africana)据说对糖尿病的饮食管理有益,但烹饪对其血糖指数的影响尚未见报道。因此,本研究调查了食用水煮面包果对链脲佐菌素(STZ)诱导的糖尿病大鼠的血清葡萄糖、葡萄糖耐量、体重和相对器官重量的影响。

方法

使用20只白化大鼠,分为四组,每组五只。第1组(正常对照组)和第2组(糖尿病对照组)给予标准大鼠颗粒饲料,而第3组(糖尿病试验组)和第4组(非糖尿病组)大鼠给予面包果。

结果

喂食标准大鼠饲料的正常血糖大鼠口服葡萄糖负荷(3 g/kg)后血糖在30分钟时达到峰值(149.75±11.12 mg/dl),但再过90分钟后降至85.25±21.05 mg/dl,而喂食面包果的正常血糖大鼠口服葡萄糖负荷后血糖在30分钟时达到峰值(146.25±15.22 mg/dl),但再过90分钟后升高(130.75±36.69 mg/dl)。与正常对照组相比,糖尿病对照组的血清葡萄糖、相对肝脏重量(RLW)和相对肾脏重量(RKW)显著升高(P<0.05),但体重显著降低;与糖尿病对照组相比,试验组的血清葡萄糖、体重、RLW和RKW无显著差异(P>0.05),与正常对照组相比,喂食面包果饮食的正常大鼠的血清葡萄糖、体重、RLW和RKW也无显著差异(P>0.05)。

结论

该研究表明,非洲面包果的传统烹饪方法会对其降血糖特性产生负面影响。

相似文献

1
Dietary intake of boiled breadfruit (Treculia africana) seeds did not improve hyperglycemia in streptozotocin induced diabetic rats: Effect on the oral glucose tolerance of normoglycemic rats.食用水煮面包果树(非洲面包树)种子对链脲佐菌素诱导的糖尿病大鼠的高血糖症并无改善作用:对正常血糖大鼠口服葡萄糖耐量的影响。
Acta Sci Pol Technol Aliment. 2017 Jan-Mar;16(1):93-99. doi: 10.17306/J.AFS.2017.0460.
2
Effect of ethanol extract of boiled breadfruit () seed on the oral glucose tolerance, lipid profile, and body weight of normoglycemic albino rats.水煮面包果种子乙醇提取物对正常血糖白化大鼠口服葡萄糖耐量、血脂水平及体重的影响。
Food Sci Nutr. 2018 Mar 25;6(4):904-911. doi: 10.1002/fsn3.626. eCollection 2018 Jun.
3
Effects of dehulled adlay on plasma glucose and lipid concentrations in streptozotocin-induced diabetic rats fed a diet enriched in cholesterol.去壳薏苡对喂食富含胆固醇饮食的链脲佐菌素诱导糖尿病大鼠血浆葡萄糖和脂质浓度的影响。
Int J Vitam Nutr Res. 2006 Sep;76(5):299-305. doi: 10.1024/0300-9831.76.5.299.
4
Impact of streptozotocin on altering normal glucose homeostasis during insulin testing in diabetic rats compared to normoglycemic rats.与血糖正常的大鼠相比,链脲佐菌素对糖尿病大鼠胰岛素测试期间改变正常葡萄糖稳态的影响。
Drug Des Devel Ther. 2015 May 5;9:2515-25. doi: 10.2147/DDDT.S79885. eCollection 2015.
5
Modulation of the lipid profile and insulin levels of streptozotocin induced diabetic rats by ethanol extract of Cnidoscolus aconitifolius leaves and some fractions: Effect on the oral glucose tolerance of normoglycemic rats.毛钩藤叶乙醇提取物及其部分馏分对链脲佐菌素诱导的糖尿病大鼠血脂谱和胰岛素水平的调节作用:对正常血糖大鼠口服葡萄糖耐量的影响。
Biomed Pharmacother. 2017 Feb;86:562-569. doi: 10.1016/j.biopha.2016.11.133. Epub 2016 Dec 23.
6
Attenuation of hyperglycemia and associated biochemical parameters in STZ-induced diabetic rats by dietary supplementation of potato peel powder.通过膳食补充马铃薯皮粉减轻链脲佐菌素诱导的糖尿病大鼠的高血糖及相关生化指标
Clin Chim Acta. 2005 Mar;353(1-2):165-75. doi: 10.1016/j.cccn.2004.10.016.
7
[Streptozotocin-induced maternal intrauterine hyperglycemia environment and its influence on development and metabolic in adult offspring with high birth weight in rats].链脲佐菌素诱导的母体子宫内高血糖环境及其对大鼠高出生体重成年后代发育和代谢的影响
Zhonghua Fu Chan Ke Za Zhi. 2012 Oct;47(10):769-76.
8
Amelioration of hyperglycaemia and its associated complications by finger millet ( Eleusine coracana L.) seed coat matter in streptozotocin-induced diabetic rats.通过在链脲佐菌素诱导的糖尿病大鼠中使用手指小米( Eleusine coracana L.)种皮物质来改善高血糖及其相关并发症。
Br J Nutr. 2010 Dec;104(12):1787-95. doi: 10.1017/S0007114510002977. Epub 2010 Oct 28.
9
Effects of Long-Term Alpha-mangostin Supplementation on Hyperglycemia and Insulin Resistance in Type 2 Diabetic Rats Induced by High Fat Diet and Low Dose Streptozotocin.长期补充α-山竹黄酮对高脂饮食联合低剂量链脲佐菌素诱导的2型糖尿病大鼠高血糖和胰岛素抵抗的影响
J Med Assoc Thai. 2015 Nov;98 Suppl 10:S23-30.
10
Combination of high-fat diet-fed and low-dose streptozotocin-treated rat: a model for type 2 diabetes and pharmacological screening.高脂饮食喂养和低剂量链脲佐菌素处理的大鼠模型:一种用于2型糖尿病和药理筛选的模型。
Pharmacol Res. 2005 Oct;52(4):313-20. doi: 10.1016/j.phrs.2005.05.004.

引用本文的文献

1
Protective effect of lyophilized extract against carboplatin-induced liver injury via inhibition of oxidative stress and inflammation in rats.冻干提取物通过抑制大鼠氧化应激和炎症对卡铂诱导的肝损伤的保护作用。
Toxicol Rep. 2024 Sep 13;13:101734. doi: 10.1016/j.toxrep.2024.101734. eCollection 2024 Dec.
2
Effect of ethanol extract of boiled breadfruit () seed on the oral glucose tolerance, lipid profile, and body weight of normoglycemic albino rats.水煮面包果种子乙醇提取物对正常血糖白化大鼠口服葡萄糖耐量、血脂水平及体重的影响。
Food Sci Nutr. 2018 Mar 25;6(4):904-911. doi: 10.1002/fsn3.626. eCollection 2018 Jun.