Barth Kelly S, Guille Constance, McCauley Jenna, Brady Kathleen T
Department of Psychiatry and Behavioral Sciences, College of Medicine, Medical University of South Carolina, Charleston, SC, United States.
Drug Alcohol Depend. 2017 Apr 1;173 Suppl 1(Suppl 1):S22-S30. doi: 10.1016/j.drugalcdep.2016.08.641.
This paper reviews the current literature on clinical guidelines, practitioner training, and government/payer policies that have come forth in response to the national rise in prescription opioid overdoses. A review of clinical opioid prescribing guidelines highlights the need for more research on safe and effective treatment options for chronic pain, improved guidance for the best management of post-operative pain, and evaluation of the implementation and impact of guideline recommendations on patient risk and outcomes. Although there is increasing attention to training in pain management in medical schools and medical residency programs, educational opportunities remain highly variable, and the need for additional clinician training in the recognition and treatment of pain as well as opioid use disorder has been recognized. Mandated use of private, federal and state educational and clinical initiatives such as Risk Evaluation and Mitigation Strategies (REMS) and Prescription Drug Monitoring Programs (PDMPs) generally increase utilization of these initiatives, but more research is needed to determine the impact of these initiatives on provider behaviors, treatment access, and patient outcomes. Finally, there is an acute need for more research on safe and effective treatments for chronic pain as well as an increased multi-level focus on improving training and access to evidence-based treatment for opioid use disorder as well as non-pharmacologic and non-interventional chronic pain treatments, so that these guideline-recommended interventions can become mainstream, accessible, first-line interventions for chronic pain and/or opioid use disorders.
本文综述了当前有关临床指南、从业者培训以及政府/支付方政策的文献,这些都是针对全国范围内处方阿片类药物过量使用情况上升而出台的。对临床阿片类药物处方指南的回顾凸显了对慢性疼痛安全有效治疗方案进行更多研究的必要性,对术后疼痛最佳管理的改进指导,以及对指南建议在患者风险和结局方面的实施情况及影响进行评估。尽管医学院校和住院医师培训项目对疼痛管理培训的关注度日益提高,但教育机会仍然差异很大,而且人们已经认识到临床医生在疼痛识别与治疗以及阿片类药物使用障碍方面还需要更多培训。强制使用诸如风险评估与缓解策略(REMS)和处方药监测项目(PDMPs)等私立、联邦和州的教育及临床举措,通常会提高这些举措的利用率,但还需要更多研究来确定这些举措对医疗服务提供者行为、治疗可及性和患者结局的影响。最后,迫切需要对慢性疼痛的安全有效治疗进行更多研究,并且需要在多个层面上加大力度,改善阿片类药物使用障碍以及非药物和非介入性慢性疼痛治疗的培训及循证治疗的可及性,以便这些指南推荐的干预措施能够成为慢性疼痛和/或阿片类药物使用障碍的主流、可及的一线干预措施。