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5 年随访中 2 种疏水性丙烯酸酯人工晶状体囊袋内行为的个体内比较。

Intraindividual comparison of capsule behavior of 2 hydrophobic acrylic intraocular lenses during a 5-year follow-up.

机构信息

From the Academic Teaching Hospital of St. Johns, Vienna, Austria.

From the Academic Teaching Hospital of St. Johns, Vienna, Austria.

出版信息

J Cataract Refract Surg. 2017 Feb;43(2):228-233. doi: 10.1016/j.jcrs.2016.12.015.

DOI:10.1016/j.jcrs.2016.12.015
PMID:28366371
Abstract

PURPOSE

To evaluate and compare the 5-year postoperative anterior (ACO) and posterior capsule opacification (PCO), the occurrence of glistenings, and the level of anterior capsule retraction after implantation of 2 designs of 1-piece hydrophobic acrylic IOLs.

SETTING

Hospital St. John, Vienna, Austria.

DESIGN

Randomized controlled prospective case series.

METHODS

Patients had an Acrysof SA60AT IOL (Group A) implanted in 1 eye and a Tecnis ZCB00 IOL (Group B) implanted in the fellow eye. At 1, 3, and 5 years, the PCO level was evaluated with the Evaluation of Posterior Capsule Opacification software. The level of ACO and capsule retraction was graded subjectively. Glistenings were scored as present or not present.

RESULTS

Fifty eyes of 25 patients were evaluated after 5 years. No significant differences in PCO scores were found between the 2 groups at all follow-up visits (1 year: 0.06 ± 0.12 [SD] versus 0.07 ± 0.13, P = .35; 3 years: 0.23 ± 0.36 versus 0.22 ± 0.32, P = .66; 5 years: 0.36 ± 0.41 versus 0.36 ± 0.54, P = .98). A significant increase in PCO score was found between 3 and 5 years (P < .01). Anterior capsule opacification was present in Group A and Group B in 18.0% and 2.7% of eyes (P = .03), in 92.0% and 24.0% of eyes, and in 100% and 52% of eyes (P < .01) at 1, 3, and 5 years, respectively. Glistenings (5 years 100%) were observed in Group A.

CONCLUSION

Both IOLs had a comparable PCO rate 5 years after surgery, although more ACO and retraction as well as glistenings were observed in Group A.

摘要

目的

评估和比较两种设计的一体式疏水性丙烯酸人工晶状体术后 5 年的前囊(ACO)和后囊混浊(PCO)、闪光的发生以及前囊收缩程度。

设置

奥地利维也纳圣约翰医院。

设计

随机对照前瞻性病例系列。

方法

患者一只眼植入 Acrysof SA60AT 人工晶状体(A 组),另一只眼植入 Tecnis ZCB00 人工晶状体(B 组)。术后 1、3 和 5 年,使用后囊混浊评估软件评估 PCO 程度。ACO 和囊收缩程度进行主观分级。闪光现象则记录为存在或不存在。

结果

25 名患者的 50 只眼在 5 年后进行了评估。两组患者在所有随访时间点的 PCO 评分均无显著差异(1 年:0.06±0.12[标准差]与 0.07±0.13,P=.35;3 年:0.23±0.36 与 0.22±0.32,P=.66;5 年:0.36±0.41 与 0.36±0.54,P=.98)。在 3 至 5 年之间,PCO 评分显著增加(P<.01)。A 组和 B 组术后 1 年、3 年和 5 年时分别有 18.0%和 2.7%(P=.03)、92.0%和 24.0%(P<.01)、100%和 52%(P<.01)的眼出现前囊混浊。闪光(5 年 100%)在 A 组中观察到。

结论

两种人工晶状体术后 5 年的 PCO 发生率相当,尽管 A 组观察到更多的 ACO 和收缩以及闪光。

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