Rivero Elena Riet Correa, Daltoé Felipe Perozzo, Mello Fernanda Weber, de Souza Carlos Eduardo Chrzanowski Pereira, Grando Liliane Janete
Department of Pathology, Federal University of Santa Catarina, Florianópolis, SC, Brazil.
Department of Pathology, Federal University of Santa Catarina, Florianópolis, SC, Brazil.
Tissue Cell. 2017 Jun;49(3):435-439. doi: 10.1016/j.tice.2017.03.005. Epub 2017 Mar 20.
The idiopathic bone cavity (IBC) is an intraosseous pseudocyst devoid of epithelial lining. Clinically, IBCs of the jaw are asymptomatic and normally found in routine radiographic exams. Although the literature regarding the content of IBCs is controversial, the final diagnosis is usually aided by the discovery of an empty cavity upon surgical exploration. The aim of this study was to perform cytological and histological analysis of IBC contents. Cytological analysis of nine cases of IBC was performed after puncture and processed by the cell block technique. Histological analysis was performed in six cases in which it was possible to collect enough material by curettage of bone walls. Remarkably, cell block analysis revealed the presence of fibrin, often arranged as a net; erythrocytes; and inflammatory cells, with a predominance of lymphocytes as well as some macrophages and neutrophils. Histological analysis showed the presence of scant connective tissue, bone trabeculae, hemorrhagic foci, and hemosiderin. Only two cases presented scattered multinucleated giant cells. Cytological evaluation of IBC content by the cell block technique might represent a useful diagnostic tool, especially in cases in which there is no available material for curettage in the cavity.
特发性骨腔（IBC）是一种无上皮衬里的骨内假性囊肿。临床上，颌骨的IBC无症状，通常在常规影像学检查中发现。尽管关于IBC内容物的文献存在争议，但最终诊断通常借助手术探查时发现的空腔得以辅助。本研究的目的是对IBC内容物进行细胞学和组织学分析。对9例IBC进行穿刺后进行细胞学分析，并采用细胞块技术进行处理。对6例通过刮除骨壁能够收集到足够材料的病例进行组织学分析。值得注意的是，细胞块分析显示存在纤维蛋白，通常呈网状排列；红细胞；以及炎性细胞，以淋巴细胞为主，还有一些巨噬细胞和中性粒细胞。组织学分析显示存在少量结缔组织、骨小梁、出血灶和含铁血黄素。仅2例出现散在的多核巨细胞。通过细胞块技术对IBC内容物进行细胞学评估可能是一种有用的诊断工具，尤其是在腔内没有可供刮除的材料的情况下。
