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肋间缝合联合肌瓣减少开胸术后疼痛:一项单盲随机临床试验

Combination of intracostal sutures with muscle flap to decrease post thoracotomy pain: A single blinded randomized clinical trial.

作者信息

Montazer Majid, Hashemzade Shahryar, Gargari Reza Movassaghi, Ramouz Ali, Sanaie Sarvin, Rasihashemi Seyed Ziaeddin

机构信息

Majid Montazer, Assistant Professor, Dept. of Cardiothoracic Surgery, Imam Reza Hospital, Tabriz University of Medical Sciences, Tabriz, Iran.

Shahryar Hashemzade, Professor, Dept. of Cardiothoracic Surgery, Imam Reza Hospital, Tabriz University of Medical Sciences, Tabriz, Iran.

出版信息

Pak J Med Sci. 2017 Jan-Feb;33(1):42-47. doi: 10.12669/pjms.331.11581.

DOI:10.12669/pjms.331.11581
PMID:28367170
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5368327/
Abstract

OBJECTIVE

To assess the efficacy of intercostal nerve protection by intercostal muscle (ICM) flap in post-thoracotomy pain improvement compared to intracostal suturing.

METHODS

In a randomized controlled trial, ninety-four patients undergoing posterolateral thoracotomy surgery were divided into two subgroups. Intracostal sutures in isolation and in combination with ICM flap techniques were used for thoracotomy closure in both groups. Numeric Pain Scale and Visual Pain Scale as pain scores were assessed on the first, second, third, fourth, fifth, sixth and seventh postoperative days and follow-up visits during the 2 week, 1, 2, 4 and 6 months after thoracotomy.

RESULTS

Out of 94 patients, 58 were male and 36 were females. While the mean age of patients in intracostal group was 45.3 ± 17.6 years, it was 47.4 ± 16.1 years in intracostal plus ICM flap group. The mean operation time for the first group was 191.0 ± 74.7 minutes, while it was 219.3 ± 68.8 minutes in the second (p>0.05). Numeric rating score and visual pain scale did not demonstrate any significant difference in pain severity on postoperative days and follow-up visits between both groups (p>0.05). Although the trend of pain reduction was significant in each group (p<0.001), the difference was not statistically significant (p>0.001).

CONCLUSION

Intracostal sutures in combination with muscle flap did not reduce postoperative pain in thoracotomy compared with intracostal sutures alone in thoracotomy closure.

摘要

目的

评估肋间肌(ICM)皮瓣保护肋间神经在开胸术后疼痛改善方面的疗效,并与肋间内缝合术进行比较。

方法

在一项随机对照试验中,94例行后外侧开胸手术的患者被分为两个亚组。两组均采用单纯肋间内缝合术以及联合肋间肌皮瓣技术进行开胸闭合术。分别在术后第1、2、3、4、5、6和7天以及开胸术后2周、1、2、4和6个月的随访中,使用数字疼痛量表和视觉疼痛量表评估疼痛评分。

结果

94例患者中,男性58例,女性36例。肋间内缝合组患者的平均年龄为45.3±17.6岁,肋间内缝合加肋间肌皮瓣组为47.4±16.1岁。第一组的平均手术时间为191.0±74.7分钟,第二组为219.3±68.8分钟(p>0.05)。数字评分量表和视觉疼痛量表显示,两组在术后各天及随访时的疼痛严重程度均无显著差异(p>0.05)。尽管每组疼痛减轻的趋势均显著(p<0.001),但差异无统计学意义(p>0.001)。

结论

在开胸闭合术中,与单纯肋间内缝合术相比,肋间内缝合联合肌皮瓣并未减轻开胸术后疼痛。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ab4e/5368327/e9fdbe1ddf51/PJMS-33-42-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ab4e/5368327/830942338cb7/PJMS-33-42-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ab4e/5368327/26cc258b3706/PJMS-33-42-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ab4e/5368327/e457d1ccc3c4/PJMS-33-42-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ab4e/5368327/e9fdbe1ddf51/PJMS-33-42-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ab4e/5368327/830942338cb7/PJMS-33-42-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ab4e/5368327/26cc258b3706/PJMS-33-42-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ab4e/5368327/e457d1ccc3c4/PJMS-33-42-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ab4e/5368327/e9fdbe1ddf51/PJMS-33-42-g004.jpg

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本文引用的文献

1
Intercostal muscle flap and intracostal suture: is two better than one?肋间肌瓣和肋内缝合:两者是否优于单一方法?
Asian Cardiovasc Thorac Ann. 2015 Mar;23(3):353. doi: 10.1177/0218492314549586. Epub 2014 Sep 2.
2
Lidocaine and pain management in the emergency department: a review article.利多卡因与急诊科疼痛管理:一篇综述文章
Anesth Pain Med. 2014 Feb 15;4(1):e15444. doi: 10.5812/aapm.15444. eCollection 2014 Feb.
3
Are intracostal sutures better than pericostal sutures for closing a thoracotomy?肋间缝合在关闭开胸切口方面是否优于肋周缝合?
Interact Cardiovasc Thorac Surg. 2012 Jun;14(6):807-15. doi: 10.1093/icvts/ivs096. Epub 2012 Mar 19.
4
Rib approximation without intercostal nerve compression reduces post-thoracotomy pain: a prospective randomized study.肋骨靠拢术不压迫肋间神经可减轻剖胸术后疼痛:一项前瞻性随机研究。
Eur J Cardiothorac Surg. 2011 Apr;39(4):570-4. doi: 10.1016/j.ejcts.2010.08.003. Epub 2010 Sep 15.
5
Intercostal muscle flap for decreasing pain after thoracotomy: a prospective randomized trial.胸腔镜手术后使用肋间肌皮瓣减轻疼痛:一项前瞻性随机试验。
Ann Thorac Surg. 2010 Jan;89(1):195-9. doi: 10.1016/j.athoracsur.2009.07.094.
6
A prospective, single-blind randomised study on the effect of intercostal nerve protection on early post-thoracotomy pain relief.一项关于肋间神经保护对减轻开胸术后早期疼痛效果的前瞻性、单盲随机研究。
Eur J Cardiothorac Surg. 2010 Apr;37(4):840-5. doi: 10.1016/j.ejcts.2009.11.004. Epub 2009 Dec 1.
7
Can chronic neuropathic pain following thoracic surgery be predicted during the postoperative period?胸外科手术后的慢性神经性疼痛能否在术后期间被预测?
Interact Cardiovasc Thorac Surg. 2009 Dec;9(6):999-1002. doi: 10.1510/icvts.2009.216887. Epub 2009 Sep 18.
8
[Effect of bilateral intercostal nerve protection on post-thoracotomy pain relief: a prospective single-blinded randomized study].[双侧肋间神经保护对开胸术后疼痛缓解的影响:一项前瞻性单盲随机研究]
Zhonghua Yi Xue Za Zhi. 2008 Mar 4;88(9):597-601.
9
Only half of the chronic pain after thoracic surgery shows a neuropathic component.胸外科手术后的慢性疼痛中,仅有一半表现出神经病理性成分。
J Pain. 2008 Oct;9(10):955-61. doi: 10.1016/j.jpain.2008.05.009. Epub 2008 Jul 16.
10
A nondivided intercostal muscle flap further reduces pain of thoracotomy: a prospective randomized trial.未分割的肋间肌皮瓣可进一步减轻开胸手术的疼痛:一项前瞻性随机试验。
Ann Thorac Surg. 2008 Jun;85(6):1901-6; discussion 1906-7. doi: 10.1016/j.athoracsur.2008.01.041.