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用于异物吸入的支气管镜检查以及雾化沙丁胺醇和布地奈德联合用药的效果

Bronchoscopy for foreign body aspiration and effects of nebulized albuterol and budesonide combination.

作者信息

Akcora Bulent, Celikkaya Mehmet Emin, Ozer Cahit

机构信息

Bulent Akcora, MD, Associate Professor, School of Medicine, Department of Pediatric Surgery, Mustafa Kemal University, 31124, Antakya, Hatay, Turkey.

Mehmet Emin Celikkaya, MD, School of Medicine, Department of Pediatric Surgery, Mustafa Kemal University, 31124, Antakya, Hatay, Turkey.

出版信息

Pak J Med Sci. 2017 Jan-Feb;33(1):81-85. doi: 10.12669/pjms.331.11297.

Abstract

OBJECTIVE

A foreign body aspiration in the tracheobronchial tree is a dangerous medical condition in the childhood period. Although rigid bronchoscopy is a safe procedure, it may cause complications. The aim of this study was to present our bronchoscopy experience and to evaluate the efficacy of pre-operative administration of nebulized albuterol and budesonide combination for reducing intra-operative complications in foreign body aspirated cases.

METHODS

In this retrospective study our pediatric cases in which a foreign body was removed from tracheobronchial tree in last 8 years were analyzed. After excluding the patients who needed emergent and negative bronchoscopies, the remaining clinically stable 84 patients were compared for the effects of preoperative administration of nebulized albuterol and budesonide combination on bronchoscopy complications.

RESULTS

There were 51 boys (60.3%) and 33 girls (39.7%). There were 38 children in the non-nebulized group and 46 children in the nebulized group. We found that the combined albuterol and budesonide nebulization decrease complications such as arterial oxygen desaturation (p<0.05), and bronchospasm (p<0.05) during the bronchoscopic intervention.

CONCLUSION

Preoperative nebulization of albuterol and budesonide combination may decrease perioperative complications of bronchoscopy.

摘要

目的

气管支气管树异物吸入是儿童期一种危险的病症。尽管硬质支气管镜检查是一种安全的操作,但仍可能引发并发症。本研究的目的是介绍我们的支气管镜检查经验,并评估术前雾化吸入沙丁胺醇和布地奈德联合用药对减少异物吸入病例术中并发症的疗效。

方法

在这项回顾性研究中,我们分析了过去8年中从气管支气管树取出异物的儿科病例。排除需要急诊和支气管镜检查结果为阴性的患者后,对其余临床稳定的84例患者术前雾化吸入沙丁胺醇和布地奈德联合用药对支气管镜检查并发症的影响进行比较。

结果

有51名男孩(60.3%)和33名女孩(39.7%)。未雾化组有38名儿童,雾化组有46名儿童。我们发现,沙丁胺醇和布地奈德联合雾化可减少支气管镜干预期间的动脉血氧饱和度下降(p<0.05)和支气管痉挛(p<0.05)等并发症。

结论

术前雾化吸入沙丁胺醇和布地奈德联合用药可能会减少支气管镜检查的围手术期并发症。

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