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维生素D水平无法预测跖骨骨折风险。

Vitamin D Levels Do Not Predict Risk of Metatarsal Fractures.

作者信息

Williams Benjamin R, Thomas Avis J, Collier Rachel C, Boffeli Troy J, Anderson Sarah A

机构信息

Department of Orthopaedic Surgery, University of Minnesota, Minneapolis, Minnesota (BRW, SAA).

HealthPartners Institute for Education and Research, Regions Hospital, St Paul, Minnesota (AJT).

出版信息

Foot Ankle Spec. 2018 Feb;11(1):37-43. doi: 10.1177/1938640017700973. Epub 2017 Apr 2.

Abstract

INTRODUCTION

In the literature, there is conflicting data regarding the relationship between vitamin D and fractures. Reports on the effects of vitamin D levels on pathologies of the foot and ankle are limited. The purpose of this study is to assess the prevalence of vitamin D insufficiency in patients who have sustained low-energy metatarsal fractures compared to foot or ankle sprains without osseous involvement.

METHODS

Between May 2012 and August 2014, vitamin D levels and demographic data were collected prospectively in a total of 99 patients; 71 with metatarsal fractures and 28 with sprains, both from a low-energy mechanism of injury. Data between the metatarsal fracture group and sprain group were compared through univariate and multivariate analyses.

RESULTS

Mean vitamin D in the fracture group was 26.9 ng/mL (range = 78.0-4.3), and in the sprain group it was 27.1 ng/mL (range = 64.1-8.3; P = .93). Vitamin D insufficiency (<30 ng/mL) was present in 47 (66%) of fracture patients and 20 (71%) of sprain patients ( P = .81).

CONCLUSION

A high incidence of hypovitaminosis D was seen in all foot and ankle patients. There was no difference in mean vitamin D level or incidence of vitamin D insufficiency between patients with metatarsal fractures or sprains resulting from similar low-energy mechanisms.

LEVELS OF EVIDENCE

Level III: Prospective, case-control study.

摘要

引言

在文献中,关于维生素D与骨折之间的关系存在相互矛盾的数据。关于维生素D水平对足踝部病变影响的报道有限。本研究的目的是评估与无骨质损伤的足踝扭伤患者相比,发生低能量跖骨骨折的患者中维生素D不足的患病率。

方法

在2012年5月至2014年8月期间,前瞻性收集了总共99例患者的维生素D水平和人口统计学数据;71例跖骨骨折患者和28例扭伤患者,均为低能量损伤机制所致。通过单因素和多因素分析比较跖骨骨折组和扭伤组的数据。

结果

骨折组的平均维生素D水平为26.9 ng/mL(范围=78.0 - 4.3),扭伤组为27.1 ng/mL(范围=64.1 - 8.3;P = 0.93)。47例(66%)骨折患者和20例(71%)扭伤患者存在维生素D不足(<30 ng/mL)(P = 0.81)。

结论

在所有足踝部患者中均观察到维生素D缺乏症的高发病率。由相似低能量机制导致的跖骨骨折或扭伤患者之间,平均维生素D水平或维生素D不足的发生率没有差异。

证据水平

III级:前瞻性病例对照研究。

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