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凸探头支气管内超声:十年进展

Convex-probe Endobronchial Ultrasound: A Decade of Progress.

作者信息

Dhooria Sahajal, Sehgal Inderpaul Singh, Aggarwal Ashutosh Nath, Agarwal Ritesh

出版信息

Indian J Chest Dis Allied Sci. 2016 Jan-Mar;58(1):21-35.

Abstract

Ever since the invention of the flexible bronchoscope, perhaps no other innovation in the field of interventional pulmonology has caused so much excitement the world over, as the convex probe endobronchial ultrasound (EBUS)-guided transbronchial needle aspiration (TBNA). While it took over a decade from 1992 to 2004 for the radial EBUS to evolve into the commercial convex probe EBUS scope, another exciting decade has gone by with the technology being thoroughly researched and appraised. The current evidence suggests that EBUS-TBNA can replace mediastinoscopy as the first investigation in the mediastinal staging of lung cancer. The use of EBUS-TBNA has been extended to several other areas including the diagnosis of undefined mediastinal lymphadenopathy, evaluation of intra-parenchymal lesions and others. In fact, EBUS-TBNA is the preferred modality for accessing mediastinal lesions in contact with the airways. The procedure not only has a high diagnostic efficiency (80%-90% for most indications) but is also safe compared to alternative options, such as image-guided fine needle aspiration and mediastinoscopy in the diagnosis of mediastinal lymphadenopathy. Apart from the traditional use of EBUS to perform TBNA, the last decade has seen the evolution of its transoesophageal use, development of novel EBUS-TBNA needles to obtain better histological specimens and a smaller EBUS scope. This review summarises the developments made in this field over the years since its inception.

摘要

自从可弯曲支气管镜发明以来,在介入肺病学领域,或许没有其他创新能像凸探头支气管内超声(EBUS)引导下经支气管针吸活检术(TBNA)那样在全球引起如此大的轰动。从1992年到2004年,径向EBUS历经十多年才发展成为商业用凸探头EBUS设备,随后又经过了令人兴奋的十年,该技术得到了充分研究和评估。目前的证据表明,EBUS-TBNA可取代纵隔镜检查,作为肺癌纵隔分期的首选检查方法。EBUS-TBNA的应用已扩展到其他多个领域,包括不明原因纵隔淋巴结肿大的诊断、肺实质内病变的评估等。事实上,EBUS-TBNA是获取与气道相邻纵隔病变的首选方式。该检查不仅诊断效率高(大多数适应证的诊断效率为80%-90%),而且与纵隔淋巴结肿大诊断中的其他替代方法(如图像引导下细针穿刺活检和纵隔镜检查)相比也更安全。除了传统的使用EBUS进行TBNA外,过去十年还见证了其经食管应用的发展、新型EBUS-TBNA针的研发以获取更好的组织学标本以及更小的EBUS设备。本综述总结了该领域自创立以来多年的发展情况。

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