Department of Obstetrics & Gynecology, The Ohio State University, Columbus, OH, United States.
Department of Gynecology & Obstetrics, Emory University, Atlanta, GA, United States.
Gynecol Oncol. 2017 Jul;146(1):3-10. doi: 10.1016/j.ygyno.2017.03.022. Epub 2017 Mar 31.
Gynecologic cancers account for ~12% of all new cancer cases in women and ~15% of all female cancer survivors. Current and continued advances within the field have resulted in long-term outcomes and a high rate of survivors. Therefore determining the most cost-effective clinical surveillance for detection of recurrence is critical. Unfortunately, there has been a paucity of research regarding the most effective strategies for surveillance after patients have achieved a complete response. Currently, most recommendations are based on retrospective studies and expert opinion. Taking a thorough history, performing a thorough examination, and educating cancer survivors about concerning symptoms are the most effective methods for the detection of most gynecologic cancer recurrences. There is very little evidence that routine cytology or imaging improves the ability to detect gynecologic cancer recurrence that will impact cure or response rates to salvage therapy. This article provides an update on surveillance for gynecologic cancer recurrence in women who have had a complete response to primary cancer therapy.
妇科癌症约占女性所有新发癌症病例的 12%,约占所有女性癌症幸存者的 15%。该领域目前和持续的进展带来了长期的结果和高生存率。因此,确定最具成本效益的临床监测以检测复发至关重要。不幸的是,关于患者获得完全缓解后进行监测的最有效策略的研究很少。目前,大多数建议都是基于回顾性研究和专家意见。详细了解病史、进行全面检查以及向癌症幸存者宣传相关症状是检测大多数妇科癌症复发的最有效方法。几乎没有证据表明常规细胞学检查或影像学检查能提高检测妇科癌症复发的能力,而这种复发会影响挽救治疗的治愈率或反应率。本文提供了一份关于女性在原发性癌症治疗后完全缓解后进行妇科癌症复发监测的更新。