Di Zazzo Antonio, Bonini Stefano, Crugliano Salvatore, Fortunato Michele
IRCCS G.B. Bietti Foundation ONLUS, via Livenza n.3, 00198, Rome, Italy.
Department of Ophthalmology, University Campus Bio-Medico of Rome, Rome, Italy.
Jpn J Ophthalmol. 2017 May;61(3):207-217. doi: 10.1007/s10384-017-0510-4. Epub 2017 Apr 3.
Pediatric keratoplasty is an immense challenge because of the technical complexity of the procedure and the high risk of rejection in young graft recipients. Our aim is to describe the major indications and appropriate timing of corneal transplantation intervention, including a report of our experience and surgical tips, in conjunction with the current literature.
Review of the literature on indications for keratoplasty in pediatric patients classified as: congenital, traumatic and acquired non-traumatic opacities. We additionally explored the challenges corneal surgeons face in performing this type of surgery and review the most pressing transplant-related problems and their management.
Outcomes after pediatric keratoplasty, in terms of visual development, restoration and clarity of the graft, are influenced by peri-operative local and systemic conditions and factors, and by intraoperative management of the transplantation procedure itself.
Pediatric corneal transplantation is a critical tool for visual restoration and development in young patients with corneal opacities, particularly during the critical period of visual development. Successful management of the significant challenges associated with pediatric keratoplasty requires customized clinical and surgical management of each patient with particular attention paid to proper post-operative rehabilitation.
由于手术技术复杂且年轻的移植受者排斥反应风险高,小儿角膜移植是一项巨大的挑战。我们的目的是结合当前文献,描述角膜移植干预的主要适应症和合适时机,包括我们的经验报告和手术技巧。
回顾关于小儿患者角膜移植适应症的文献,这些患者分为:先天性、外伤性和后天性非外伤性混浊。我们还探讨了角膜外科医生在进行此类手术时面临的挑战,并回顾了最紧迫的移植相关问题及其管理方法。
小儿角膜移植后的结果,在视觉发育、移植片的恢复和清晰度方面,受围手术期局部和全身状况及因素以及移植手术本身的术中管理影响。
小儿角膜移植是患有角膜混浊的年轻患者视觉恢复和发育的关键工具,尤其是在视觉发育的关键时期。成功应对小儿角膜移植相关的重大挑战需要对每位患者进行定制的临床和手术管理,特别要注意适当的术后康复。