Krylova L V, Khasanova D R
Department of Medical Rehabilitation of Patients with Central Nervous System Lesion, Hospital of War Veterans, Naberezhnye Chelny, Russia.
Kazan State Medical University of the Ministry of Healse of the Russian Federation, Kazan, Russia.
Zh Nevrol Psikhiatr Im S S Korsakova. 2017;117(2):42-48. doi: 10.17116/jnevro20171172142-48.
To assess the efficacy of botulinum toxin therapy for different patterns of poststroke spasticity.
Thirty-nine patients with poststroke spasticity were examined. Rehabilitation included 4 treatment courses of inpatient rehabilitation during 9 month usinga multidisciplinary team approach. Botulinum toxin therapy was included in the program. The individual program was developed taking into account the dynamics of a pathological spastic pattern.
The transformation of the pathological movement pattern was observed during the rehabilitation using botulinum toxin. The best positive changes, including an improvement of the upper extremity function, walk and a decrease in the degree of paresis, was identified when botulinum toxin therapy was used in early stages of neurorehabilitation (1-3 month after stroke).
评估肉毒杆菌毒素疗法对不同类型中风后痉挛的疗效。
对39例中风后痉挛患者进行检查。康复治疗包括采用多学科团队方法，在9个月内进行4个疗程的住院康复治疗。该项目中包含肉毒杆菌毒素疗法。根据病理性痉挛模式的动态变化制定个体化方案。
在使用肉毒杆菌毒素进行康复治疗期间，观察到病理性运动模式发生了转变。当在神经康复早期（中风后1 - 3个月）使用肉毒杆菌毒素疗法时，发现了最佳的积极变化，包括上肢功能、步行能力的改善以及轻瘫程度的降低。
