Department of Gynecologic Oncology, Tepecik Education and Research Hospital, Izmir, Turkey.
Oncol Res Treat. 2017;40(4):203-206. doi: 10.1159/000458440. Epub 2017 Mar 21.
We compared the disease free-survival (DFS) and overall survival (OS) rates of patients with high-grade serous primary fallopian tube cancer (HG-sPFTC) and high-grade serous epithelial ovarian cancer (HG-sEOC).
22 early-stage cancer patients (International Federation of Gynecology and Obstetrics (FIGO) stages I-II) with HG-sPFTC were retrospectively evaluated. In addition, 44 control patients diagnosed with HG-sEOC were matched to these patients with respect to tumor stage at diagnosis. All patients underwent complete surgical staging, followed by adjuvant chemotherapy. Kaplan-Meier curves were used to generate survival data.
The mean age of HG-sPFTC patients was 59.4 ± 6.2 years, and that of HG-sEOC patients 55.2 ± 11.0 years (p = 0.002). All patients underwent 6 cycles of platinum-based adjuvant chemotherapy. All operations were optimal. The 5-year DFSs were 77.3% for HG-sPFTC patients and 75% for HG-sEOC patients (p = 1.00).The 5-year OS rates were 81.8% in women with HG-sPFTC and 77.3% in those with HG-sEOC (p = 0.75).
The DFS and OS rates of patients with early-stage (FIGO stages I and II) HG-sPFTC and HG-sEOC were similar. The surgical and adjuvant therapy management of these malignancies should be similar.
我们比较了高级别浆液性原发性输卵管癌（HG-sPFTC）和高级别浆液性上皮性卵巢癌（HG-sEOC）患者的无病生存（DFS）和总生存（OS）率。
回顾性评估了 22 名早期癌症患者（国际妇产科联合会（FIGO）分期 I-II 期）的 HG-sPFTC。此外，根据诊断时的肿瘤分期，对这些患者匹配了 44 名诊断为 HG-sEOC 的对照患者。所有患者均接受了全面的手术分期，然后接受辅助化疗。Kaplan-Meier 曲线用于生成生存数据。
HG-sPFTC 患者的平均年龄为 59.4 ± 6.2 岁，HG-sEOC 患者为 55.2 ± 11.0 岁（p = 0.002）。所有患者均接受了 6 个周期的铂类辅助化疗。所有手术均为最佳手术。HG-sPFTC 患者的 5 年 DFS 为 77.3%，HG-sEOC 患者为 75%（p = 1.00）。HG-sPFTC 患者的 5 年 OS 率为 81.8%，HG-sEOC 患者为 77.3%（p = 0.75）。
早期（FIGO 分期 I 和 II）HG-sPFTC 和 HG-sEOC 患者的 DFS 和 OS 率相似。这些恶性肿瘤的手术和辅助治疗管理应相似。
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