神经递质受体与G蛋白的相互作用：受体反应机制中的关键环节。
Neurotransmitter receptor interactions with G-proteins: a critical link in receptor response mechanisms.
作者信息
Severson J A
机构信息
Amersham Corporation, Arlington Heights, IL 60005.
出版信息
Neurobiol Aging. 1988 Jan-Feb;9(1):67-8. doi: 10.1016/s0197-4580(88)80026-5.
PMID:2837673
Abstract
The interaction of membrane bound receptors with guanine nucleotide binding regulatory proteins is necessary for the transduction of many extracellular signals across the cell membrane. Age-related impairments of this interaction illustrate that the efficiency of receptor effector coupling is complex, and is an additional factor for consideration in the future study of receptor mediated functions.
摘要
膜结合受体与鸟嘌呤核苷酸结合调节蛋白的相互作用对于许多细胞外信号跨细胞膜的转导是必要的。这种相互作用与年龄相关的损伤表明受体效应器偶联的效率是复杂的，并且是未来受体介导功能研究中需要考虑的另一个因素。
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