不同利尿剂对普通人群尿钙排泄的影响。

Effects of different diuretics on urinary calcium excretion in a general population.

作者信息

Goulding A, Spears G F, Simpson F O

出版信息

Aust N Z J Med. 1978 Oct;8(5):474-8. doi: 10.1111/j.1445-5994.1978.tb02585.x.

DOI:10.1111/j.1445-5994.1978.tb02585.x

Abstract

Calcium excretion by users and non-users of thiazide diuretics and frusemide was studied during a health survey. Men taking thiazides excreted less calcium than age- and weight-matched controls. Both men and women taking thiazides excreted less calcium relative to sodium than controls. Women taking thiazides excreted significantly less calcium than women taking frusemide. Both men and women taking thiazides excreted less calcium relative to creatinine than sex-matched groups taking frusemide.

摘要

在一项健康调查中，对使用和未使用噻嗪类利尿剂及速尿的人群的钙排泄情况进行了研究。服用噻嗪类药物的男性排出的钙比年龄和体重匹配的对照组少。服用噻嗪类药物的男性和女性相对于钠的钙排泄量均低于对照组。服用噻嗪类药物的女性排出的钙明显少于服用速尿的女性。服用噻嗪类药物的男性和女性相对于肌酐的钙排泄量均低于服用速尿的性别匹配组。