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胫骨骨折内固定术后感染:医疗资源利用及相关费用分析

Infection after fracture fixation of the tibia: Analysis of healthcare utilization and related costs.

作者信息

Metsemakers Willem-Jan, Smeets Bart, Nijs Stefaan, Hoekstra Harm

机构信息

University Hospitals Leuven, Department of Trauma Surgery, B-3000 Leuven, Belgium; KU Leuven, University of Leuven, Department of Development and Regeneration, B-3000 Leuven, Belgium.

University Hospitals Leuven, Care Program Management, B-3000 Leuven, Belgium.

出版信息

Injury. 2017 Jun;48(6):1204-1210. doi: 10.1016/j.injury.2017.03.030. Epub 2017 Mar 22.

Abstract

INTRODUCTION

One of the most challenging complications in musculoskeletal trauma surgery is the development of infection after fracture fixation (IAFF). It can delay healing, lead to permanent functional loss, or even amputation of the affected limb. The main goal of this study was to investigate the total healthcare costs and length-of-stay (LOS) related to the surgical treatment of tibia fractures and furthermore identify the subset of clinical variables driving these costs within the Belgian healthcare system. The hypothesis was that deep infection would be the most important driver for total healthcare costs.

PATIENTS AND METHODS

Overall, 358 patients treated operatively for AO/OTA type 41, 42, and 43 tibia fractures between January 1, 2009 and January 1, 2014 were included in this study. A total of 26 clinical and process variables were defined. Calculated costs were limited to hospital care covered by the Belgian healthcare financing system. The five main cost categories studied were: honoraria, materials, hospitalization, day care admission, and pharmaceuticals.

RESULTS

Multivariate analysis showed that deep infection was the most significant characteristic driving total healthcare costs and LOS related to the surgical treatment of tibia fractures. Furthermore, this complication resulted in the highest overall increase in total healthcare costs and LOS. Treatment costs were approximately 6.5-times higher compared to uninfected patients.

CONCLUSION

This study shows the enormous hospital-related healthcare costs associated with IAFF of the tibia. Treatment costs for patients with deep infection are higher than previously mentioned in the literature. Therefore, future research should focus more on prevention rather than treatment strategies, not only to reduce patient morbidity but also to reduce the socio-economic impact.

摘要

引言

肌肉骨骼创伤手术中最具挑战性的并发症之一是骨折内固定术后感染(IAFF)。它会延迟愈合,导致永久性功能丧失,甚至需要截肢。本研究的主要目的是调查与胫骨骨折手术治疗相关的总医疗费用和住院时间(LOS),并进一步确定比利时医疗体系中导致这些费用的临床变量子集。假设是深部感染将是总医疗费用的最重要驱动因素。

患者与方法

本研究纳入了2009年1月1日至2014年1月1日期间接受手术治疗的358例AO/OTA 41、42和43型胫骨骨折患者。总共定义了26个临床和过程变量。计算的费用仅限于比利时医疗融资体系覆盖的住院治疗。研究的五个主要费用类别是:酬金、材料、住院、日间护理入院和药品。

结果

多变量分析表明,深部感染是与胫骨骨折手术治疗相关的总医疗费用和住院时间的最显著特征驱动因素。此外,这种并发症导致总医疗费用和住院时间的总体增幅最高。与未感染患者相比,治疗费用高出约6.5倍。

结论

本研究表明胫骨IAFF与医院相关的医疗费用巨大。深部感染患者的治疗费用高于文献中先前所述。因此,未来的研究应更多地关注预防而非治疗策略,不仅要降低患者发病率,还要减少社会经济影响。

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