Grabenwöger F, Dock W, Appel W, Pinterits F
II. Chirurgische Universitätsklinik, Wien.
Rofo. 1988 Jun;148(6):615-8. doi: 10.1055/s-2008-1048260.
A prospective study of the results of fibrinolytic therapy in 87 patients was carried out with particular reference to the type of fibrinolytic agent. The primary success rate using urokinase was 78%, which was markedly greater than the 44% success rate when using streptokinase. An attempt was also made to evaluate the effect of other factors, such as the extent and duration of the occlusion. Long term results, as might have been expected, were directly related to the primary success rate. If fibrinolytic therapy resulted in fairly normal vasculature, the long-term results were satisfactory in 79%, whereas unsatisfactory reconstruction of the vascular bed produced a satisfactory long-term result in only 30%.
对87例患者进行了纤维蛋白溶解疗法结果的前瞻性研究，特别提及了纤维蛋白溶解剂的类型。使用尿激酶的主要成功率为78%，明显高于使用链激酶时44%的成功率。还尝试评估其他因素的影响，如阻塞的程度和持续时间。正如预期的那样，长期结果与主要成功率直接相关。如果纤维蛋白溶解疗法使血管系统相当正常，79%的长期结果是令人满意的，而血管床重建不理想时，只有30%能产生令人满意的长期结果。
