Kim Min Kyoung, Jung Yeon Soo, Chon Seung Joo, Yun Bo Hyon, Cho Sihyun, Choi Young Sik, Lee Byung Seok, Seo Seok Kyo
Department of Obstetrics and Gynecology, Severance Hospital, Yonsei University College of Medicine, Seoul, Korea.
Institute of Women's Life Medical Science, Yonsei University College of Medicine, Seoul, Korea.
J Korean Med Sci. 2017 May;32(5):830-834. doi: 10.3346/jkms.2017.32.5.830.
The common causes of postmenopausal bleeding (PMB), according to the data from the western world, are atrophy, hormone replacement therapy (HRT), endometrial cancer, etc. We conducted a retrospective study to assess whether the causes of PMB in Korean postmenopausal women are similar to those already known. This retrospective study used 10-year medical records (March 2005 to December 2014) of 792 PMB women in the Yonsei University Health System. The data were divided into 2 categories by 5-year intervals to compare the differences between the 2 periods. The most common cause of PMB in Korean women was atrophy (51.1%). Polyps and HRT were the second, followed by anticoagulant medications, cervical cancer, and endometrial cancer. The proportion of patients with cervical cancer significantly decreased during the second half of the decade (8.7% vs. 5.2%; P = 0.048). Although no significant change was noted for HRT, its rank was higher during the latter 5-year period. Only the most common cause of PMB was the same as the conventional data. Interestingly, the proportion of patients with cervical cancer decreased during the latter half of the decade, reflecting the changes in the nation's cancer prevalence rate, while the use of HRT increased.
根据西方世界的数据,绝经后出血(PMB)的常见原因包括萎缩、激素替代疗法(HRT)、子宫内膜癌等。我们进行了一项回顾性研究,以评估韩国绝经后女性PMB的原因是否与已知原因相似。这项回顾性研究使用了延世大学医疗系统中792名PMB女性的10年医疗记录(2005年3月至2014年12月)。数据按5年间隔分为两类,以比较两个时期之间的差异。韩国女性PMB最常见的原因是萎缩(51.1%)。息肉和HRT位居第二,其次是抗凝药物、宫颈癌和子宫内膜癌。十年后半期宫颈癌患者的比例显著下降(8.7%对5.2%;P = 0.048)。虽然HRT没有显著变化,但其排名在后一个5年期间更高。只有PMB最常见的原因与传统数据相同。有趣的是,十年后半期宫颈癌患者的比例下降,反映了该国癌症患病率的变化,而HRT的使用增加。