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体重对关节镜下距骨骨软骨重建的影响。

The Impact of Weight on Arthroscopic Osteochondral Talar Reconstruction.

作者信息

Usuelli Federico Giuseppe, Maccario Camilla, Ursino Chiara, Serra Nicola, D'Ambrosi Riccardo

机构信息

1 IRCCS Istituto Ortopedico Galeazzi, UO CASCO, Piede e Caviglia, Milan, Italy.

2 Dipartimento di Scienze Biomediche per la Salute, Università degli Studi di Milano, Milan, Italy.

出版信息

Foot Ankle Int. 2017 Jun;38(6):612-620. doi: 10.1177/1071100717695349. Epub 2017 Feb 1.

Abstract

BACKGROUND

The purpose of the study was to assess the functional and radiologic outcomes after AT-AMIC (arthroscopic talus autologous matrix-induced chondrogenesis) in 2 weight groups of patients with osteochondral lesions of the talus (OLTs): patients with BMI <25 (Healthy Weight Group [HG]) and with BMI ≥25 (Overweight Group [OG]).

METHODS

Thirty-seven patients were evaluated. HG was composed of 21 patients (BMI = 21.90 ± 1.94), whereas OG consisted of 16 patients (BMI = 27.41 ± 1.98). All patients were treated with AT-AMIC repair for OLTs. Magnetic resonance imaging (MRI), computed tomography (CT), Visual Analgoue Scale (VAS) for pain, American Orthopaedic Foot & Ankle Society (AOFAS) Ankle and Hindfoot score and Short-Form Health Survey (SF-12) were administered preoperatively (T) and at 6 (T), 12 (T), and 24 (T) months postoperatively.

RESULTS

In both groups, we found a significant difference for clinical and radiologic parameters with analysis of variance for repeated measures through 4 time points ( P < .001). In HG, AOFAS increased at every follow-up ( P < .05), whereas in OG, AOFAS improved only between T and T ( P = .0104). In OG we found a significant difference comparing CT and MRI at each follow-up; in HG this difference was found only at T ( P < .0001) and T ( P = .0492). Finally, OG presented a significantly larger lesion measured with MRI at T ( P = .033).

CONCLUSIONS

OLTs in overweight patients were characterized by a larger preoperative size. At final follow-up, both groups showed a significant clinical improvement. AT-AMIC can be considered a safe and reliable procedure, regardless of weight, with a significant improvement also in quality of life.

LEVEL OF EVIDENCE

Level III, comparative study.

摘要

背景

本研究旨在评估距骨骨软骨损伤(OLT)患者两个体重组在接受关节镜下距骨自体基质诱导软骨形成术(AT-AMIC)后的功能和影像学结果:体重指数(BMI)<25的患者(健康体重组[HG])和BMI≥25的患者(超重组[OG])。

方法

对37例患者进行评估。HG组由21例患者组成(BMI = 21.90±1.94),而OG组由16例患者组成(BMI = 27.41±1.98)。所有患者均接受OLT的AT-AMIC修复治疗。术前(T0)以及术后6个月(T1)、12个月(T2)和24个月(T3)进行磁共振成像(MRI)、计算机断层扫描(CT)、疼痛视觉模拟量表(VAS)、美国矫形足踝协会(AOFAS)踝关节和后足评分以及简明健康调查(SF-12)。

结果

在两组中,通过对4个时间点的重复测量方差分析,我们发现临床和影像学参数存在显著差异(P <.001)。在HG组中,每次随访时AOFAS评分均增加(P <.05),而在OG组中,AOFAS评分仅在T0和T1之间有所改善(P = .0104)。在OG组中,我们发现在每次随访时CT和MRI之间存在显著差异;在HG组中,这种差异仅在T0(P <.0001)和T2(P = .0492)时发现。最后,在T0时,OG组经MRI测量的损伤明显更大(P = .033)。

结论

超重患者的OLT特点是术前损伤尺寸更大。在末次随访时,两组均显示出显著的临床改善。无论体重如何,AT-AMIC均可被视为一种安全可靠的手术方法,并且在生活质量方面也有显著改善。

证据水平

III级,比较研究。

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