Houdek Matthew T, Watts Chad D, Wyles Cody C, Trousdale Robert T, Milbrandt Todd J, Taunton Michael J
From the Department of Orthopedic Surgery, Mayo Clinic, Rochester, MN.
J Am Acad Orthop Surg. 2017 May;25(5):381-388. doi: 10.5435/JAAOS-D-16-00437.
Currently, few data examine the use of total knee arthroplasty (TKA) in patients with cerebral palsy (CP). This study reviewed the outcomes of TKA in patients with CP compared with a matched cohort undergoing TKA for primary osteoarthritis.
Over a 28-year period, 15 TKAs in patients with a diagnosis of CP were identified. The cohort was 53% men, with a mean age of 58 years. Patients with CP were matched 1:2 based on age, sex, body mass index, and year of surgery with a group of patients undergoing TKA for osteoarthritis.
No difference was reported in implant survival (P = 0.27) or revision surgery (P = 0.79) between groups. All patients were ambulatory postoperatively, and significant increases were noted in the Knee Society score (P < 0.0001) and functional assessment (P = 0.003).
TKA is a safe, durable procedure in patients with CP to improve pain and function.
目前，很少有数据研究全膝关节置换术（TKA）在脑瘫（CP）患者中的应用。本研究回顾了CP患者TKA的结果，并与一组因原发性骨关节炎接受TKA的匹配队列进行了比较。
在28年的时间里，确定了15例诊断为CP的患者接受TKA。该队列中男性占53%，平均年龄58岁。CP患者根据年龄、性别、体重指数和手术年份与一组因骨关节炎接受TKA的患者按1:2进行匹配。
两组之间在植入物存活率（P = 0.27）或翻修手术（P = 0.79）方面没有差异。所有患者术后均能行走，膝关节协会评分（P < 0.0001）和功能评估（P = 0.003）均有显著提高。
TKA对于CP患者是一种安全、持久的手术，可改善疼痛和功能。
