Ciocan Răzvan A, Bolboacă Sorana D, Rădulescu Şerban, Stancu Bogdan, Ciocan Andra, Gherman Claudia D
Department of Medical Informatics and Biostatistics, Iuliu Haţieganu University of Medicine and Pharmacy Cluj-Napoca, 6 Louis Pasteur St., Cluj-Napoca, 400685 Romania.
Department of Medical Informatics and Biostatistics, Iuliu Haţieganu University of Medicine and Pharmacy Cluj-Napoca, 6 Louis Pasteur St., Cluj-Napoca, 400685.
Folia Med (Plovdiv). 2017 Mar 1;59(1):14-22. doi: 10.1515/folmed-2017-0014.
The present study aimed at identifying the pattern of patients with critical limb ischemia (CLI) compared with those with peripheral arterial occlusive disease (PAOD).
A four-year retrospective study was conducted with patients hospitalized in the Second Surgical Clinic at the Emergency County Hospital Cluj-Napoca. The medical charts of patients with PAOD (n=466) and CLI (n=223) were reviewed and data were collected.
The study included 689 patients; mean age 67 years for PAOD patients and 65 years for CLI patients. A significantly higher percentage of patients were male in both groups (79.25%, P < 0.0001). Most of the patients in both groups had received at least a secondary education (P < 0.0001). Most of the subjects in both groups were smokers (>71.30%) with no difference between groups (P = 0.566). No significant differences were found between the groups in comorbidities (diabetes, arterial blood hypertension, cardiac ischemia, rhythm disorders, P > 0.05). There were more CLI patients that were overweight than overweight patients with PAOD (P = 0.0004). High serum cholesterol (>200 mg/dL) and triglycerides (>150 mg/dL) levels were found in the CLI group (P < 0.05). Age was identified as a risk factors for amputation (OR = 1.03, 95%Cl [1.01-1.05], P = 0.0012).
The profile of a patient with critical limb ischemia and peripheral arterial occlusive disease is a 65-67-year-old male smoker with at least a secondary education. The CLI patient is overweight with pathological serum levels of cholesterol and triglycerides.
本研究旨在确定与外周动脉闭塞性疾病(PAOD)患者相比,严重肢体缺血(CLI)患者的特征模式。
对在克卢日-纳波卡县急救医院第二外科诊所住院的患者进行了一项为期四年的回顾性研究。回顾了PAOD患者(n = 466)和CLI患者(n = 223)的病历并收集了数据。
该研究纳入了689名患者;PAOD患者的平均年龄为67岁,CLI患者为65岁。两组中男性患者的比例均显著更高(79.25%,P < 0.0001)。两组中的大多数患者至少接受过中等教育(P < 0.0001)。两组中的大多数受试者均为吸烟者(>71.30%),组间无差异(P = 0.566)。两组在合并症(糖尿病、动脉高血压、心脏缺血、心律失常,P > 0.05)方面未发现显著差异。CLI超重患者多于PAOD超重患者(P = 0.0004)。CLI组中发现血清胆固醇(>200 mg/dL)和甘油三酯(>150 mg/dL)水平较高(P < 0.05)。年龄被确定为截肢的危险因素(OR = 1.03,95%CI [1.01 - 1.05],P = 0.0012)。
严重肢体缺血和外周动脉闭塞性疾病患者的特征是一名65 - 67岁、至少接受过中等教育的男性吸烟者。CLI患者超重,胆固醇和甘油三酯水平呈病理性升高。